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Microneedling for Transepidermal Drug Delivery on Stretch Marks

Reference work entry
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Part of the Clinical Approaches and Procedures in Cosmetic Dermatology book series (CAPCD)

Abstract

Stretch marks (SMs) are a well-recognized, common skin condition that rarely cause any significant medical problems but are often a significant source of distress to those affected. The origins of SM are poorly understood, and a number of treatment modalities (Elsaie et al. 2009) are available for their treatment, yet none of them is consistently effective, and no single therapy is considered to be consensus for this problem. Multiple sittings of treatments such as chemical peelings, microdermabrasion, nonablative and ablative laser techniques, and light and radiofrequency devices are performed to improve the SM appearance. Microneedling and transepidermal drug delivery together are a new modality of treatment for SM. It is based on stimulation of collagen production and enhancement of the penetration of certain active substances across the skin with which it is possible to achieve satisfactory results.

Keywords

Microneedling Transdermal drug delivery Transepidermal drug delivery Stretch marks Collagen 

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Clinica Vida – Cosmetic, Laser and Mohs Surgery CenterSão PauloBrazil

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