Gait Changes in Skeletal Dysplasia
Skeletal dysplasias form a group of conditions that affect the musculoskeletal system resulting in gait changes. These conditions share some common gait patterns, such as short stride length, low gait velocity, and increased forward pelvic tilt. Increased pelvic rotation is also a common mechanism, used to increase the step length. However, specific gait deviations are found in each condition. Knee axis deviations in the coronal plane are well-described clinical features in these conditions. While bilateral knee varus is common in achondroplasia, bilateral knee valgus is a shared finding between diastrophic dysplasia and Morquio syndrome. Sagittal kinematic deviations in stance show normal knee flexion in achondroplasia and increased knee flexion values in diastrophic dysplasia and Morquio syndrome.
Due to the different, multilevel gait deviations that follow the multilevel deformity found in skeletal dysplasia, instrumented, three-dimensional, gait analysis becomes a helpful tool to evaluate the individual aspects of the deformity and to approach the patient with an accordingly customized management plan.
KeywordsSkeletal dysplasia Achondroplasia Diastrophic dysplasia Morquio syndrome Spondyloepiphyseal dysplasia
- Anderson IJ, Goldberg RB, Marion RW et al (1990) Spondyloepiphyseal dysplasia congenita: genetic linkage to type II collagen (COL2AI). Am J Hum Genet 46(5):896–901Google Scholar
- Bayhan IA, Er MS, Nishnianidze T et al (2015) Gait pattern and lower extremity alignment in children with diastrophic dysplasia. J Pediatr Orthop. https://doi.org/10.1097/BPO.0000000000000530
- Egginton R, Newman C, Walsh M et al (2006) Kinematic characteristics of Achondroplasia. Gait Posture. Elsevier 24(2):S249–S250Google Scholar
- Kopits SE (1988) Thoracolumbar kyphosis and lumbosacral hyperlordosis in achondroplastic children. Basic Life Sci 48:241–255Google Scholar