Forensic DNA Evidence
Synonyms
DNA analysis; DNA profiling; DNA typing
Definition
Deoxyribonucleic acid (DNA) is a large molecule present in all living cells (e.g., animals, plants, viruses). As a tape allows the storage of a recording, DNA allows the storage of genetic information. It consists of two long chains of nucleotides twisted in a double helix. There are four types of nucleotides designed by the name of their bases: Adenine (A), Guanine (G), Cytosine (C), and Thymine (T). The genetic information is encoded in the sequence of nucleotides of the DNA molecule. Part of its name originates from its localization in the nuclei of the cell. However, the acronym is also used for mitochondrial DNA (mtDNA), which is the DNA present in the mitochondria of the cells. It is transmitted only by the mother.
Introduction
Although DNA profiling has high discriminating power and can help in establishing the biological identity of a person, it is not used as a biometric yet. Indeed, the results of the analysis are...
References
- 1.R. Coquoz, F. Taroni, Preuve par l’ADN -la génétique au service de la justice (Presses Polytechniques et Universitaires Romandes, Lausanne, 2006)Google Scholar
- 2.J.M. Butler, Forensic DNA typing, in Biology, Technology, and Genetics of STR Markers, 2nd edn. (Elsevier Academic, Burlington, 2005)Google Scholar
- 3.P. Gill, J. Whitaker, C. Flaxman, N. Brown, J. Buckleton, In investigation of the rigor of interpretation rules for STRs derived from less than 100 pg of DNA. Foreusic Sci. Intern. 112(1), 17–40 (2000)Google Scholar
- 4.B. Caddy, G.R. Linacre, A.M.T. Taylor, A review of the science of low template DNA analysis (2008). http://police.homeoffice.gov.uk/publications/operational-policing/Review_of_Low_Template_DNA_1.pdf?view=Binary
- 5.R. Cook, I.W. Evett, G. Jackson, P.J. Jones, J.A. Lambert, A hierarchy of propositions: deciding which level to address in casework. Sci. Justice 38,231–240 (1998)Google Scholar
- 6.J. Buckleton, C. Triggs, S.J. Walsh, Forensic DNA Evidence Interpretation (CRC, Boca Raton, 2005)Google Scholar
- 7.T. Bevel, R. Gardner, Blood Pattern Analysis with an Introduction to Crime Scene Reconstruction, 3rd edn. (CRC, New York, 2008)Google Scholar
- 8.I.W. Evett, B.S. Weir, Interpreting DNA Evidence – Statistical Genetics for Forensic Scientists (Sinauer, Sunderland, 1998)Google Scholar
- 9.C.G.G. Aitken, F. Taroni, Statistics and the Evaluation of Evidence for Forensic Scientists, 2nd edn. (Wiley, Chichester, 2004)MATHGoogle Scholar
- 10.National Research Council, Committee on DNA Technology in Forensic Science, Board on Biology, Commission on Life Sciences, in DNA Technology in Forensic Science (National Academy, Washington, 1992)Google Scholar
- 11.National Research Council, Committee on DNA Forensic Science, The Evaluation of Forensic DNA Evidence (National Academy, Washington, 1996)Google Scholar
- 12.R. Williams, P. Johnson, Forensic DNA databasing: a european perspective. Interim Report. Unviersity of Durham, Durham (2005)Google Scholar
- 13.B. Robertson, G.A. Vignaux, Interpreting Evidence – Evaluating Forensic Science in the Courtroom (Wiley, Chichester, 1995)Google Scholar