Large-Scale Models of the Olfactory Bulb
The olfactory bulb is a small and self-contained neural system of the forebrain that is pivotally involved in producing the sense of the smell. Large-scale models of the olfactory bulb reconstruct extensive portion of it, including the main neuron populations, such as mitral, tufted, and granule cells, along with their connectivity. They are constituted by four components: (i) a model of odor inputs, (ii) cell models reproducing the salient properties of the main neuron types, (iii) the organization in glomeruli, and (iv) models of the feedforward and/or feedback inhibition mediated via glomerular and granule cell layers, respectively. Therefore, large-scale models of the olfactory bulb realize powerful frameworks to simulate the...
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