Encyclopedia of Computational Neuroscience

Living Edition
| Editors: Dieter Jaeger, Ranu Jung

Theta-Gamma Cross-Frequency Analyses (Hippocampus)

  • Robson Scheffer-Teixeira
  • Adriano B. L. TortEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-7320-6_100658-1



Brain oscillations of different frequencies can coexist and influence each other. A cross-frequency interaction occurs when a feature from one oscillation (i.e., instantaneous amplitude, phase, or frequency) depends on a feature from another oscillation at a distinct frequency. These phenomena have been collectively called cross-frequency coupling (CFC). There are multiple types of CFC, such as phase-amplitude coupling, amplitude-amplitude coupling, and n:m phase-locking. Several metrics have been devised to quantify CFC.

Detailed Description

The study of the electrical activity produced by the brain dates back to Richard Caton in 1875, who employed a galvanometer to record from the cortex of rabbits (Geddes 1987). Neuronal spikes and extracellular field potentials have been since recorded from several brain regions of different species, and...
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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Robson Scheffer-Teixeira
    • 1
  • Adriano B. L. Tort
    • 1
    Email author
  1. 1.Brain InstituteFederal University of Rio Grande do NorteNatalBrazil

Section editors and affiliations

  • Frances K. Skinner
    • 1
    • 2
    • 3
  1. 1.Krembil Research InstituteTorontoCanada
  2. 2.PhysiologyUniversity of TorontoTorontoCanada
  3. 3.Medicine (Neurology)University of TorontoTorontoCanada