Maternal Obesity and ASD Risk
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Obesity is a nutritional and metabolic life-course condition with excessive accumulation of adipose tissue that affects health adversely. Body mass index (BMI) calculated as weight in kilograms divided by height in meters squared was used for the definition of obesity. By this measure, obesity is defined as a BMI ≥30 kg/m2 for adults. Furthermore, BMI values were classified in the following categories: underweight <18·5; normal 18.5–24.9; overweight 25–29.9; obese class I 30–34.9, obese class II 35–39.9; obese class III ≥ 40 according to the National Institute of Health guidelines on obesity and overweight (NIH 1998). While there is no existing definition of maternal obesity during pregnancy, a maternal prepregnancy BMI is used for the classification.
In 2011, Dodds et al. (2011) published their study quantifying the relationship between prenatal, obstetric, and neonatal factors and autism risk. They first reported that prepregnancy weight of 90 kg or...
References and Reading
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