Living Reference Work Entry

Encyclopedia of Metagenomics

pp 1-7

Date: Latest Version

MEMOSys: Platform for Genome-Scale Metabolic Models

  • Stephan PabingerAffiliated withDivision of Bioinformatics, Biocenter, Innsbruck Medical UniversityAIT – Austrian Institute of Technology, Health & Environment Department, Molecular Diagnostics Email author 
  • , Zlatko TrajanoskiAffiliated withDivision of Bioinformatics, Biocenter, Innsbruck Medical University


Bioinformatics platform for genome-scale metabolic models


MEMOSys is a web-based platform for constructing, managing, and storing genome-scale metabolic models. It provides sophisticated query and data exchange mechanisms, offers an integrated version control system, and allows researchers to easily compare models. MEMOSys is freely available at http://​www.​icbi.​at/​memosys under the GNU Affero General Public License.


Driven by recent innovations in sequencing technology, genome-scale metabolic models have been compiled for a number of different organisms (Henry et al. 2010). Each model is in general a network consisting of metabolites that are connected by reactions. Genome-scale models include all reactions occurring in a living organism and are primarily reconstructed using the annotated genome and literature information. Metabolic models can be used to provide an alternative approach for integrating large amounts of data about biological systems to gain no ...

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