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Definition
Arsenic is a ubiquitous element in the Earth’s crust. Exposure to this metalloid may induce a variety of responses including oxidative stress, metabolic alterations, growth inhibition, and eventually cell death. A complex enzyme network metabolizes arsenic, inducing the expression of stress proteins. Stress proteins are molecules produced after exposure to a physical or chemical agent. The most common stress proteins induced by arsenic exposure are metallotionein, ubiquitin, and heat shock proteins (HSPs).
Introduction
In nature, arsenic is found in several forms including oxides, chlorine, or sulfur compounds. Water is the most common medium for environmental distribution of arsenic (Del Razo et al. 2001). Exposure to arsenic produces a variety of stress responses in cells including morphological, physiological, biochemical, and molecular alterations. Arsenic (As) may enter an organism through epithelial exposure or...
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Rios-Perez, A., Morales-Rico, P., Muñoz, B. (2013). Arsenic-Induced Stress Proteins. In: Kretsinger, R.H., Uversky, V.N., Permyakov, E.A. (eds) Encyclopedia of Metalloproteins. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1533-6_479
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DOI: https://doi.org/10.1007/978-1-4614-1533-6_479
Publisher Name: Springer, New York, NY
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