Encyclopedia of Metalloproteins

2013 Edition
| Editors: Robert H. Kretsinger, Vladimir N. Uversky, Eugene A. Permyakov

Porous Silicon for Drug Delivery

  • Hélder A. SantosEmail author
  • Jarno Salonen
  • Luis M. Bimbo
Reference work entry
DOI: https://doi.org/10.1007/978-1-4614-1533-6_447

Synonyms

Definition

 Porous silicon (PSi) refers to a material containing interconnected networks of empty holes (pores) in a Si structure, rendering the material with a large surface-to-volume ratio properties. PSi materials are classified according to pore diameter, that can vary from a few nanometers to a few micrometers depending on the fabrication parameters. Most commonly, the PSi structure is referred as mesoporous (pores with diameters between 2 and 50 nm). Sometimes the word “nanoporous” is used instead of mesopores to emphasize the nanometric dimension of the pores. The volumetric fraction of empty space (voids) in the structure of the material is called porosity. The internal surface area of PSi per volume unit can be as large as 500 m2/cm3 and can act as reservoirs for storing therapeutic compounds for drug delivery applications.

Fabrication Procedures and Role in Drug...

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References

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Hélder A. Santos
    • 1
    Email author
  • Jarno Salonen
    • 2
  • Luis M. Bimbo
    • 1
  1. 1.Division of Pharmaceutical TechnologyUniversity of HelsinkiHelsinkiFinland
  2. 2.Laboratory of Industrial Physics, Department of PhysicsUniversity of TurkuTurkuFinland