(−)-Nicotinoyl-2-phenyl-2-hydroxyethylamine

CAS Registry Number: 168780-03-8 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Amine, Amide, and Sulfur Containing Alkaloids

Biological sources: Oxytropis muricata, O. puberula

C₁₄H₁₄N₂O₂: 242.1055

Mp: 157–158°C (Me₂CO) [1]

[α]_D −25° (MeOH) [1]

UV: 210, 256 sh [1]

IR: 3330, 1650 [1]

MSm/z: 242(M⁺, 0.5), 224(2), 136(100), 135(70), 123(16), 118(9), 107(28), 106(52), 105(11), 79(35), 78(30), 77(22) [1]

¹H NMR (DMSO-d₆): 3.30, 3.48(each 1H, m, 2H-1), 4.77(1H, m, H-2), 5.49(1H, d, J = 2.5, OH), 7.22(1H, t, J = 7, H-6), 7.31(2H, t, J = 7, H-5, H-7), 7.35(2H, d, J = 7, H-4, H-8), 7.45(1H, dd, J = 5, 8, H-5′), 8.13(1H, dt, J = 8, 1.3, H-4′), 8.65(1H, dd, J = 5, 1.3, H-6′), 8.67(1H, t, J = 5, NH), 8.95(1H, d, J = 1.3, H-2′) [1]