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Taxonomy: Physicochemical and Pharmacological Properties of Sesquiterpene Esters – The Bicyclic Sesquiterpene Esters – Caryophyllanes – Monoesters

Biological sources: Lychnophora martiana Gardner [1]; L. salicifolia Mart. [2]

C₁₇H₂₄O₄: 292.1675

[α]²⁴ (λ, nm): + 40.5° (589), + 42.0° (578), + 48.0° (546), + 84.6° (436) (c 3.2, CHCl₃) [2]

Mp: 168°C (hexane ether – MeOH) [1]; 170°C (Et₂O) [2]

IR (KBr): 3350, 1680, 1630 [1]; 3300–2600, 1690, 1640, 905 [2]

MS: 292 [M]⁺ [1]

MS: 292.167 [M]⁺ (0.2), 250 (3), 232 (12), 217 (6), 43 (100) [2]

¹H NMR (270 MHz, CDCl₃, TMS): 1.05 (3H, s, H-13), 1.19 (3H, s, H-12), 1.6 (2H, m, H-10), 2.2 (3H, m, H-9β, H-7α, H-4b), 2.89 (1H, d, J = 11, H-1α), 3.5 (2H, m, H-7β, H-4a), 4.99 (1H, br s, H-15b), 5.16 (1H, br s, H-15a), 5.70 (1H, dt, J = 11; 6; H-8), 6.29 (1H, dd, J = 10; 6, H-5) [1]

¹H NMR(270 MHz): 1.05 (3H, s, H-13), 1.13 (3H, s, H-12), 1.53 (1H, dd, H-10α), 1.64 (1H, dd, H-10β), 1.83 (1H, ddd, H-9), 2.05 (3H, s, OAc), 2.10 (1H,...