Reference Work Entry

Encyclopedia of Systems Biology

pp 888-892

High-Performance Computing, Structural Biology

  • Piercarlo DondiAffiliated withDepartment of Computer Engineering and Systems Science, University of Pavia Email author 
  • , Luca LombardiAffiliated withDepartment of Computer Engineering and Systems Science, University of Pavia

Synonyms

Parallel computing

Definition

High Performance Computing (HPC) refers to technologies used for implementing systems able to execute time expensive elaborations and to manage a huge amount of data in a small amount of time. HPC solutions are commonly exploited in different scientific fields that require the solution of complex mathematical models, like climatology, physics, medicine, or biology. One of the most recent innovations, which presents a good compromise between hardware cost and performances, is the use of the GPU for parallel computation. This technology supplies promising results in simulation and modeling of biological systems and in real-time medical analysis.

Characteristics

Parallel Computing

HPC (Large-Scale and High-Performance Computing) comes from the need of more and more great computational power to elaborate complex mathematical models and to evaluate new scientific theories. Technical and physical constraints limit the maximum ...

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