Encyclopedia of Systems Biology

2013 Edition
| Editors: Werner Dubitzky, Olaf Wolkenhauer, Kwang-Hyun Cho, Hiroki Yokota

Metabolic Networks

  • Andreas Dräger
  • Hannes Planatscher
Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-9863-7_1277



Metabolic networks are interconnected pathways of biochemical reactions within living cells through which building blocks or compounds necessary for cellular functioning are assembled (anabolism) or energy and matter are produced by breaking down biomolecules (catabolism). These pathways are often organized as cycles or chains of coupled reactions, in which the product of one reaction serves as the substrate of the succeeding reaction. Although all reactions are reversible in principle, thermodynamic gradients within metabolic reactions often promote one direction, yielding a flux through the metabolic pathways. In many cases distinct pathways or reactions exist for contrary flows of matter. All processes within a metabolic network are temporally and spatially organized. Often cells contain several compartments which separate parts of its reaction network into...

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© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  1. 1.Center for Bioinformatics, University of TuebingenTuebingenGermany
  2. 2.Natural and Medical Sciences Institute at the University of TuebingenReutlingenGermany