Encyclopedia of Behavioral Medicine

2013 Edition
| Editors: Marc D. Gellman, J. Rick Turner

Heart Disease and Cardiovascular Reactivity

Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-1005-9_804



There has been a long-standing notion that exaggerated responses to mental stress are linked to the development of future heart disease (Hamer & Malan, 2010). Although not clinically meaningful in themselves, if heightened responses to stress are elicited on a regular basis, they might become clinically relevant over time. Existing work has largely focused on cardiovascular reactivity to stress as a tool to predict future risk. Blood pressure and heart rate responses to mental stress are largely augmented by the sympathetic nervous system and release of catecholamines. The issue of whether stress reactivity contributes to the progression of underlying disease or only to the incidence of clinical cardiac events has led to research involving indicators of subclinical disease. Several studies have indicated that heightened blood pressure and heart rate responses to laboratory-induced stressors predict future progression of subclinical...

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References and Readings

  1. Chida, Y., & Steptoe, A. (2010). Greater cardiovascular responses to laboratory mental stress are associated with poor subsequent cardiovascular risk status: A meta-analysis of prospective evidence. Hypertension, 55(4), 1026–1032.PubMedCrossRefGoogle Scholar
  2. Gianaros, P. J., & Sheu, L. K. (2009). A review of neuroimaging studies of stressor-evoked blood pressure reactivity: Emerging evidence for a brain-body pathway to coronary heart disease risk. NeuroImage, 47(3), 922–936.PubMedCrossRefGoogle Scholar
  3. Hamer, M., & Malan, L. (2010). Psychophysiological risk markers of cardiovascular disease. Neuroscience and Biobehavioral Reviews, 35(1), 76–83.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, New York 2013

Authors and Affiliations

  1. 1.Epidemiology and Public Health, Division of Population HealthUniversity College LondonLondonUK