Reference Work Entry

Blaustein’s Pathology of the Female Genital Tract

pp 909-928

Nonspecific Tumors of the Ovary, Including Mesenchymal Tumors

  • Aleksander TalermanAffiliated withDepartment of Surgical Pathology, Thomas Jefferson University Hospital Email author 
  • , Russell VangAffiliated withDepartment of Pathology, Division of Gynecologic Pathology, The Johns Hopkins Medical Institutions


The tumors discussed in this chapter comprise a heterogeneous group of neoplasms that are not specific to the ovary. They are uncommon in this location, occurring much more frequently in other parts of the body. Consequently, whenever they are encountered in the ovary, these tumors pose difficult problems in diagnosis, histogenesis, behavior, and therapy for the pathologist and clinician. These neoplasms must be differentiated from primary ovarian neoplasms containing mesenchymal tissue, as well as from metastatic and disseminated neoplasms affecting the ovary. Thus, mesenchymal neoplasms nonspecific to the ovary must be differentiated primarily from teratomatous neoplasms containing large amounts of mature or immature mesenchymal elements and from the malignant mesodermal mixed müllerian (mesodermal) tumors (MMMT), which are composed of different malignant connective tissue elements in addition to their malignant epithelial components. Tumors of teratomatous origin containing mesenchymal tissue are described in Chap. 16, Germ Cell Tumors of the Ovary, and MMMTs/carcinosarcomas, endometrioid stromal sarcomas, and adenosarcoma are discussed in Chap. 14, Surface Epithelial Tumors of the Ovary.