Exonuclease
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First Online:
DOI: https://doi.org/10.1007/978-1-4020-6754-9_5707
An enzyme that digests a polynucleotide chain beginning at either the 5′ (RecJ) or the 3′ terminus (Exo I, VI, X) or from both ends (ExoVII). Among these only ExoX degrades double-strand DNA. Exonucleases may degrade misaligned tandem repeats and thus favor DNA stability (Feschenko VV et al 2003 Proc Nat Acad Sci USA 100:1134). Bal1, recombination mechanisms, endonuclease, restriction enzymes, mismatch repair, RecA-independent recombination; Grunberg-Manago M 1999 Annu Rev Genet 33:193; Shevelev IV, Hübscher U 2002 Nature Rev Mol Cell Biol 3:364.
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