The excessive expression of cystathionine β-synthetase seems to be linked to decreased atherosclerosis and higher survival rates, if stricken by acute myeloblastic leukemia (AML) in Down syndrome (see Fig. C207). Its anomalies may cause homocystinuria. homocystinuria, AML; Ge Y et al 2001 J Biol Chem 276:43570.
