Reference Work Entry

Encyclopedia of Genetics, Genomics, Proteomics and Informatics

pp 1928-1929


Tandem Repeat

Adjacent direct repeats (such as ATG ATG ATG) of any size and number. In Caenorhabditis elegans, 2.7% of the genome involves tandem repeats and these occur on the average once per 3.6 kb. Comparative genomic analysis of breeds of dogs and other species indicate that increase or decrease of tandem repeats affect the apparently rapid evolution of morphological traits, particularly in the Alx-4 (aristaless-like 4) and Runx-2 (runt-related transcription factor) involved in skull and limb morphology, respectively (Fondon JW Garner HR 2004 Proc Natl Acad Sci USA 101:18058). repeat inverted, Drosophila , runt; https://​tandem.​bu.​edu/cgi-bin/trdb/trdb.exe.

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