RNA polymerase involved in the synthesis of transfer RNA, 5S rRNA, 7S rRNA and U6 snRNA in eukaryotes. Transcription of pol III is higher during S and G2 phases of the cell cycle than during G1. Many neoplastic cells display high pol III activity indicating that protein synthesis is demanded for tumorous growth. The RET protein appears to be a suppressor of increased pol III activity.  Trna,  ribosomal RNA,  ribosomes,  La; Geiduschek EP, Tocchini-Valentini GP 1988 Annu Rev Biochem 57:873; Huang Y, Maraia RJ 2001 Nucleic Acids Res 29:2675.