Lobectomy
Definition
A “lobectomy” is a surgical procedure for removing a diseased or damaged portion of a solid tissue such as lung, liver, or brain. Removal of damaged and usually swollen parts of the brain may be necessary in more severe TBI, neoplasms, intracranial hematomas, and occasionally in cases of severe brain infection. Untreated, such conditions can cause increased intracranial pressure and further damage to nearby areas of brain resulting in further morbidity as well as increasing mortality risk.
Historical Background
Lobectomies of the brain for treatment of seizures have been studied the most. These procedures are performed when the subject does not respond to medication, or is unable to tolerate medication side effects, or has seizures caused by structural abnormalities in the brain and usually involve the temporal or frontal lobes. The recognized behavioral changes that occur after these procedures can be expected after partial or total lobectomies for any indication.
Current...
References and Readings
- Alpherts, W. C. J., Vermeulen, J., Hendriks, M. P. H., Franken, M. L. O., van Rijen, P. C., Lopes da Silva, F. H., et al. (2004). Long-term effects of temporal lobectomy on intelligence. Neurology, 62, 607–611.PubMedGoogle Scholar
- Brierley, B., Medford, N., Shaw, P., & David, A. S. (2004). Emotional memory and perception in temporal lobectomy patients with amygdala damage. Journal of Neurology Neurosurgery and Psychiatry, 75, 593–599.Google Scholar
- Bullock, M. R., Chesnut, R., Ghajar, J., Gordon, D., Hartl, R., Newell, D. W., et al., Surgical Management of Traumatic Brain Injury Author Group. (2006). Surgical management of traumatic parenchymal lesions. Neurosurgery, 58(3), S25–S46.PubMedGoogle Scholar
- Carson, B. S., Sr. (2000). Indications and outcomes for lobectomy, corpus callosotomy, and hemispherectomy in pediatric neurosurgical patients. Clinical Neurosurgery, 47, 385–399.PubMedGoogle Scholar
- Contardi, S., Rubboli, G., Giulioni, M., Michelucci, R., Pizza, F., Gardella, E., et al. (2007). Charles Bonnet syndrome in hemianopsia, following antero-mesial temporal lobectomy for drug-resistant epilepsy. Epileptic Disorders, 9(3), 271–275.PubMedGoogle Scholar
- Jang, S. H., You, S. H., & Ahn, S. H. (2007). Neurorehabilitation-induced cortical reorganization in brain injury: a 14-month longitudinal follow-up study. NeuroRehabilitation, 22(2), 117–122.PubMedGoogle Scholar
- Mayanagi, Y., Watanabe, E., Nagahori, Y., & Nankai, M. (2001). Psychiatric and neuropsychological problems in epilepsy surgery: analysis of 100 cases that underwent surgery. Epilepsia, 42(6), 19–23.PubMedGoogle Scholar