Phenelzine
Reference work entry
DOI: https://doi.org/10.1007/978-0-387-79948-3_1692
Generic Name
Phenelzine
Brand Name
Nardil, Nardelzine
Class
Monoamine oxidase inhibitor (MAOI)
Proposed Mechanism(s) of Action
Reduces the breakdown of norepinephrine, serotonin, and dopamine via the inhibition of monoamine oxidase.
Indication
Depression (atypical, nonendogenous, neurotic).
Off Label Use
Treatment-resistant depression, panic disorder, and social anxiety disorder.
Side Effects
Serious
Hypertensive crisis, seizures, liver toxicity, and mania.
Common
Orthostatic hypotension, syncope, sexual dysfunction, nausea, weight gain, blurred vision, dizziness, sedation, headache, sleep disturbance, tremor, weakness, and fatigue.
References and Readings
- Physicians’ Desk Reference (62nd ed.). (2007). Montvale, NJ: Thomson PDR.Google Scholar
- Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide(2nd ed.). New York, NY: Cambridge University Press.Google Scholar
Additional Information
- Drug Interaction Effects: http://www.drugs.com/drug_interactions.html
- Drug Molecule Images: http://www.worldofmolecules.com/drugs/
- Free Drug Online and PDA Software: www.epocrates.com
- Gene-Based Estimate of Drug interactions: http://mhc.daytondcs.com:8080/cgibin/ddiD4?ver=4&task=getDrugList
- Pill Identification: http://www.drugs.com/pill_identification.html
Copyright information
© Springer Science+Business Media, LLC 2011