Short Description or Definition
Retrograde amnesia is the inability to retrieve experiences, facts, or concepts that were encountered prior to the causative disease or trauma. The loss of memories may be partial or complete; it frequently shows a temporal gradient with a dense loss for information acquired immediately prior to the onset of amnesia, and progressively decreasing loss for information acquired more remotely. It occurs in the amnesic syndromes, various forms of dementia, and head trauma.
Historical Background
Retrograde amnesia was described on several occasions in the eighteenth century – a notable example being Benjamin Franklin’s observation that electric shock could lead to loss of memory for the event. The first systematic study of retrograde amnesia came with Ribot’s (1882) treatise on disordered memory in which he formulated the law of regression, now known as Ribot’s law, that states that recently formed memories are the fastest to disappear. Contemporary cognitive...
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References and Readings
DeRenzi, E., Liotti, M., & Nichelli, P. (1987). Semantic amnesia with preservation of autobiographical memory: A case report. Cortex, 23, 578–597.
Kopelman, M. D. (2000a). Focal retrograde amnesia and the attribution of causality: An exceptionally critical review. Cognitive Neuropsychology, 17, 585–621.
Kopelman, M. D. (2000b). The neuropsychology of remote memory. In L. S. Cermak (Ed.), Handbook of neuropsychology (Vol. 2, pp. 251–280). Amsterdam: Elsevier Science.
Levine, B., Black, S. E., Cabeza, R., Sinden, M., Mcintosh, A. R., Toth, J. P., et al. (1998). Episodic memory and the self in a case of isolated retrograde amnesia. Brain, 121, 1951–1973.
Moscovitch, M., Nadel, L., Winocur, G., Gilboa, A., & Rosenbaum, R. S. (2006). The cognitive neuroscience of remote episodic, semantic and spatial memory. Current Opinion in Neurobiology, 16, 179–190.
Moscovitch, M., Yaschyshyn, T., Ziegler, M., & Nadel, L. (2000). Remote episodic memory and retrograde amnesia: Was Endel Tulving right all along? In E. Tulving (Ed.), Memory, consciousness and the brain (pp. 331–345). Philadelphia, PA: Psychology Press.
O’Connor, M., Butters, N., Miliotis, P., Eslinger, P., & Cermak, L. S. (1992). The dissociation of anterograde and retrogradeamnesia in a patient with herpes encephalitis. Journal of Clinical and Experimental Neuropsychology, 14, 159–178.
Rempel-Clower, N.L., Zola, S.M., Squire, L.R., & Amaral, D. G. (1996). Three cases of enduring memory impairment after bilateral damage limited to the hippocampal formation. The Journal of Neuroscience, 16(16), 5233–5255.
Ribot, T. A. (1882). Diseases of memory. New York, Appleton-Century-Crofts.
Squire, L. R., & Alvarez, P. (1995). Retrograde amnesia and memory consolidation: A neurobiological perspective. Current Opinions in Neurobiology, 5, 169–177.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer Science+Business Media, LLC
About this entry
Cite this entry
Lafleche, G., Verfaellie, M. (2011). Retrograde Amnesia. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, New York, NY. https://doi.org/10.1007/978-0-387-79948-3_1152
Download citation
DOI: https://doi.org/10.1007/978-0-387-79948-3_1152
Publisher Name: Springer, New York, NY
Print ISBN: 978-0-387-79947-6
Online ISBN: 978-0-387-79948-3
eBook Packages: Behavioral Science