Reference Work Entry

Encyclopedia of Clinical Neuropsychology

pp 1342-1342

Interictal Behavior Syndrome

  • Christine J. Weber-MihailaAffiliated withNeuropsychologist, Northeast Regional Epilepsy Group


Geschwind syndrome (or Waxman–Geschwind Syndrome); Interictal personality syndrome; Temporal lobe syndrome


A distinct syndrome of behavior described initially by Stephen Waxman and Norman Geschwind that occurs interictally (i.e., between seizure events) in some patients with complex partial seizures with involvement of the temporal lobe (usually associated the most with individuals with left temporal lobe epilepsy). These changes have been described to include alterations in sexual behavior (usually hyposexuality or decreased interest in sexual behavior), increased religiosity (hyper-religiosity and/or hyper-morality), increased verbal output, hypergraphia, circumstantial thinking, stickiness or viscosity in thinking and social interactions, and deepened emotionality.

Current Knowledge

Although it is widely known that psychiatric comorbidity among individuals with epilepsy is high compared with the general population, the existence of a ...

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