Thrombophilic Disorders
Synonyms
Definition
Thrombophilic Disorder is a broad term for disorders and conditions in which the blood forms clots easily or excessively, also known as thrombophilia. These disorders may result in an increased risk of blood clot formation in the veins and arteries, which can contribute to complications resulting in severe injury or death. Thrombophilic disorders can be due to either hereditary or acquired factors.
Description
Blood clotting is a natural and normal process in which the blood cells and proteins group together to form a clump, or clot, to slow or inhibit bleeding after a blood vessel has been injured. Most blood clots tend to dissolve naturally through cellular activity. Some people, however, may experience thrombophilia, where blood clots form without the presence of injury at increased rates. These blood clots can travel through the blood stream to other locations, resulting in a thrombosis, or a blood clot...
References
- 1.American College of Obstetricians and Gynecologists (ACOG). (2000). Thromboembolism in pregnancy. ACOG Practice Bulletin, 19.Google Scholar
- 2.Heit, J. A. (2007). Thrombophilia: common questions on laboratory assessment and management. Hematology American Society of Hematology Education Program, 2007, 127–135.Google Scholar
- 3.James, A. H., Tapson, V., & Goldhaber, S. (2005). Thrombosis during pregnancy and the postpartum period. American Journal of Obstetrics and Gynecology, 193(1), 216–219.PubMedGoogle Scholar