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Quality of Life Measures in Fibromyalgia

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Handbook of Disease Burdens and Quality of Life Measures

Abstract:

Fibromyalgia (FM) is a chronic, widespread and painful disorder of affecting approximately 2–3% of the general population, with an approximately 90% female preponderance. Health-related quality of life (HRQoL) outcome assessment is crucial in patients with FM because of their multiple symptoms, which include chronic pain, fatigue, weakness, hyperalgesia, secondary depression and allodynia. These can produce substantial work disability and disruptions in quality of life, with impaired social and family functioning. The diverse symptomatology of patients with FM may be assessed holistically using HRQoL questionnaires. These questionnaires can be classified into generic measures and disease-specific measures. SF-36 and EQ-5D represent the generic tools most commonly used in FM studies, but other questionnaires include the Sickness Impact Profile (SIP), Nottingham Health Profile (NHP), Health Utilities Index (HUI) and Quality of Well Being Index (QWB). The fibromyalgia-specific instruments most commonly used are the Fibromyalgia Impact Questionnaire (FIQ) and FibroFatigue Scale (FFS). To date, few cost-utility analyses exist. Examples include EQ-5D and SF-6D. Using these questionnaires it has been shown that patients with FM perform worse than other chronic pain patients, such as those with rheumatoid arthritis and chronic back pain, specifically when vitality, bodily pain, mental health, social functioning, mobility, usual activities, pain/discomfort and anxiety/depression scores were analyzed. The impact of illness, adjusted for co-morbidities, increased in younger adults but the symptomatology decreased with age.

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Abbreviations

ACR:

American College of Rheumatology

AIMS:

arthritis impact measurement scales

CFS:

chronic fatigue syndrome

EQ-5D:

Euroqol five item Questionnaire

EQ-5D VAS:

The EQ-5D Visual Analogue Scale

FFS:

the fibromyalgia and chronic fatigue syndrome rating scale

FIQ:

The Fibromyalgia Impact Questionnaire

FM:

Fibromyalgia

HAQ:

Stanford Health Assessment Questionnaire

NHP:

Nottingham Health Profile

QALYs:

quality-adjusted life-years

QWB:

quality of well being index

HRQoL:

health-related quality of life

HUI:

the health utilities index

15-D:

the health state descriptive system questionnaire

SF-36:

Short Form Health Survey questionnaire with 36 questions

SF-6D:

6-item Short Form Health Survey Questionnaire

SIP:

sickness impact profile

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© 2010 Springer Science+Business Media LLC

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Gusi, N., Olivares, P.R., Carmelo Adsuar, J., Paice, A., Tomas-Carus, P. (2010). Quality of Life Measures in Fibromyalgia. In: Preedy, V.R., Watson, R.R. (eds) Handbook of Disease Burdens and Quality of Life Measures. Springer, New York, NY. https://doi.org/10.1007/978-0-387-78665-0_231

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  • DOI: https://doi.org/10.1007/978-0-387-78665-0_231

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-78664-3

  • Online ISBN: 978-0-387-78665-0

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