Nevoid hypermelanosis
Reference work entry
DOI: https://doi.org/10.1007/3-540-29668-9_1892
Synonym(s)
Lentiginous hyperpigmentation; linear and whorled nevoid hypermelanosis
Definition
Congenital disorder characterized by streaks and whorls of macular hyperpigmentation along Blaschko's lines
Pathogenesis
Presumed to represent somatic mosaicism
Clinical manifestation
Onset in first few weeks of life; irregular swirls of macular hyperpigmentation, following Blaschko's lines; may cross the midline and be discontinuous; may fade somewhat as child ages
Differential diagnosis
Incontinentia pigmenti; hypomelanosis of Ito; Nevus of Ota and Ito; post-inflammatory hyperpigmentation; nevus spilus
Therapy
No effective therapy
References
- Schepis C, Siragusa M, Alberti A, Cavallari V (1996) Linear and whorled nevoid hypermelanosis in a boy with mental retardation and congenital defects. International Journal of Dermatology 35(9):654–655PubMedCrossRefGoogle Scholar
Copyright information
© Springer-Verlag 2004