Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine

2006 Edition
| Editors: Detlev Ganten, Klaus Ruckpaul, Walter Birchmeier, Jörg T. Epplen, Klaus Genser, Manfred Gossen, Birgit Kersten, Hans Lehrach, Hartmut Oschkinat, Patrizia Ruiz, Peter Schmieder, Erich Wanker, Christiane Nolte

Chromodomain

Reference work entry
DOI: https://doi.org/10.1007/3-540-29623-9_6498

Definition

Chromodomains are highly conserved sequence motifs that have been identified in a variety of animal and plant species. A chromodomain harbours a methylated lysine residue. Chromodomain proteins appear to be either structural components of large macromolecular chromatin complexes, or proteins involved in remodelling the chromatin structure. Some chromodomains have a binding affinity for histone H3 methylated on lysine 9, whereas others have RNA binding capacity.

 Chromatin Acetylation Chromatin Remodelling Methylation of Proteins Nucleosomes

Copyright information

© Springer-Verlag 2005