These are chemokine receptor blocking agents that do not induce receptor-mediated signal transduction. Numerous antagonists have been generated by means of chemokine structure modifications. For potential use in the treatment of inflammatory diseases small molecular weight (non-peptide) compounds are favored over chemokine-derived inhibitors.
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© 2005 Springer-Verlag
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(2005). Chemokine Receptor Antagonists. In: Vohr, HW. (eds) Encyclopedic Reference of Immunotoxicology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27806-0_246
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DOI: https://doi.org/10.1007/3-540-27806-0_246
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-44172-4
Online ISBN: 978-3-540-27806-1
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