Chemokine Receptor Antagonists

Reference work entry

These are chemokine receptor blocking agents that do not induce receptor-mediated signal transduction. Numerous antagonists have been generated by means of chemokine structure modifications. For potential use in the treatment of inflammatory diseases small molecular weight (non-peptide) compounds are favored over chemokine-derived inhibitors.

 Immune Cells, Recruitment and Localization of

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© Springer-Verlag 2005