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Optical Coherence Tomography

  • Ruikang K. Wang
  • Valery V. Tuchin
Reference work entry
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Abstract

The fundamental aspects of optical coherence tomography and brief description of its applications in medicine and biology are presented. The impact of multiple scattering in tissues on the OCT imaging performances, and the developments in reducing the overwhelming multiple scattering effects and improving imaging capabilities by the use of immersion technique are discussed. A novel technique based on the usc of biocompatible and osmotically active chemical agents to impregnate the tissue and to enhance the OCT images is described. The mechanisms for improvements of imaging depth and contrast are discussed, primarily through the experimental examples.

Key words

optical coherence tomography multiple scattering osmotically active agents refractive index matching skin mucosa colon tooth ceramics 
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© Kluwer Academic Publishers 2004

Authors and Affiliations

  • Ruikang K. Wang
    • 1
  • Valery V. Tuchin
    • 2
  1. 1.Cranfield University at SilsoeBedfordshireUK
  2. 2.Saratov State UniversitySaratovRussian Federation

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