Skip to main content
SpringerLink
Log in

Liquid Extraction: Folch

  • Living reference work entry
  • First Online:
Encyclopedia of Lipidomics

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

Abbreviations

DAG:

Diacylglycerol

GC-MS:

Gas chromatography/mass spectrometry

LC-MS:

Liquid chromatography–mass spectrometry

MTBE:

Methyl-tert-butyl ether

PA:

Phosphatidyl acid

PC:

Phosphatidylcholine

PE:

Phosphatidylethanolamine

PG:

Phosphatidylglycerol

PI:

Phosphatidylinositol

TAG:

Triacylglycerol

References

  • Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol. 1959;37(8):911–7.

    Article  CAS  PubMed  Google Scholar 

  • Bloor WR. The determination of small amounts of lipid in blood plasma. J Biol Chem. 1928;77(1):53–73.

    CAS  Google Scholar 

  • Byeon SK, Lee JY, Moon MH. Optimized extraction of phospholipids and lysophospholipids for nanoflow liquid chromatography-electrospray ionization-tandem mass spectrometry. Analyst. 2012;137(2):451–8.

    Article  CAS  PubMed  Google Scholar 

  • Elias H, Lorenz S, Winnen G. Das Experiment: 100 Jahre Nernstscher Verteilungssatz. Chemie in unserer Zeit. 1992;26(2):70–5.

    Article  CAS  Google Scholar 

  • Folch J. The isolation of phosphatidyl serine from brain cephalin, and identification of the serine component. J Biol Chem. 1941;139(2):973–4.

    CAS  Google Scholar 

  • Folch J. The chemical structure of phosphatidyl serine. J Biol Chem. 1948;174(2):439–50.

    CAS  PubMed  Google Scholar 

  • Folch J. Brain diphosphoinositide, a new phosphatide having inositol metadiphosphate as a constituent. J Biol Chem. 1949;177(2):505–19.

    CAS  PubMed  Google Scholar 

  • Folch J, Lees M. Proteolipides, a new type of tissue lipoproteins: their isolation from brain. J Biol Chem. 1951;191(2):807–17.

    CAS  PubMed  Google Scholar 

  • Folch J, Schneider HA. An amino acid constituent of ox brain cephalin. J Biol Chem. 1941;137(1):51–62.

    CAS  Google Scholar 

  • Folch J, Woolley DW. Inositol, a constituent of a brain phosphatide. J Biol Chem. 1942;142(2):963–4.

    CAS  Google Scholar 

  • Folch J, Arsove S, Meath JA. Isolation of brain strandin, a new type of large molecule tissue component. J Biol Chem. 1951a;191(2):819–31.

    CAS  PubMed  Google Scholar 

  • Folch J, Ascoli I, Lees M, Meath JA, LeBaron FN. Preparation of lipide extracts from brain tissue. J Biol Chem. 1951b;191(2):833–41.

    CAS  PubMed  Google Scholar 

  • Folch J, Lees M, Stanley GHS. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem. 1957;226(1):497–50.

    CAS  PubMed  Google Scholar 

  • Hansen H, Wang T, Dolde D, Xin H. Tocopherol and annatto tocotrienols distribution in laying-hen body. Poult Sci. 2015;94(10):2421–33.

    Article  CAS  PubMed  Google Scholar 

  • Iverson S, Lang SC, Cooper M. Comparison of the bligh and dyer and folch methods for total lipid determination in a broad range of marine tissue. Lipids. 2001;36(11):1283–7.

    Article  CAS  PubMed  Google Scholar 

  • Lees MB, Pope A. Jordi Folch-Pi. Biographical memoirs, vol. 79. National Academy of Sciences of the United States of America; 2001. p. 135–56, ISBN: 0-309-7572-6.

    Google Scholar 

  • Matyash V, Liebisch G, Kurzchalia TV, Shevchenko A, Schwudke D. Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics. J Lipid Res. 2008;49(5):1137–46.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Maudens KE, Wille SM, Lambert WE. Traces of phosgene in chloroform: consequences for extraction of anthracyclines. J Chromatogr B Analyt Technol Biomed Life Sci. 2007;848(2):384–90.

    Article  CAS  PubMed  Google Scholar 

  • Patterson RE, Ducrocq AJ, McDougall DJ, Garrett TJ, Yost RA. Comparison of blood plasma sample preparation methods for combined LC–MS lipidomics and metabolomics. J Chromatogr B. 2015;1002:260–6.

    Article  CAS  Google Scholar 

  • Ragab S, Abd Elghaffar S, El-Metwally T, Badr G, Mahmoud M, Omar H. Effect of a high fat, high sucrose diet on the promotion of non-alcoholic fatty liver disease in male rats: the ameliorative role of three natural compounds. Lipids Health Dis. 2015;14(1):83.

    Article  PubMed  PubMed Central  Google Scholar 

  • Ruiz-López N, Martinez-Force E, Garcés R. Sequential one-step extraction and analysis of triacylglycerols and fatty acids in plant tissues. Anal Biochem. 2003;317(2):247–54.

    Article  PubMed  Google Scholar 

  • Noorden RV, Maher B, Nuzzo R. The top 100 papers. Nature. 2014;514(7524):550–3.

    Article  PubMed  Google Scholar 

  • Segura J, Calvo L, Óvilo C, González-Bulnes A, Olivares A, Cambero MI, et al. Alternative method for intramuscular fat analysis using common laboratory equipment. Meat Sci. 2015;103:24–7.

    Article  CAS  PubMed  Google Scholar 

  • Sperry WM, Brand FC. The determination of total lipides in blood serum. J Biol Chem. 1955;213(1):69–76.

    CAS  PubMed  Google Scholar 

  • Turk E. Phosgene from chloroform. Chem Eng News. 1998;76(9):6.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Research Center Borstel, Parkallee 1-40, 23845, Borstel, Germany

    Lars F. Eggers & Dominik Schwudke

Authors
  1. Lars F. Eggers
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Dominik Schwudke
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Dominik Schwudke .

Editor information

Editors and Affiliations

  1. Yong Loo Lin School of Medicine Centre for Life Sciences, Singapore, Singapore

    Markus R. Wenk

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer Science+Business Media Dordrecht

About this entry

Cite this entry

Eggers, L.F., Schwudke, D. (2016). Liquid Extraction: Folch. In: Wenk, M. (eds) Encyclopedia of Lipidomics. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7864-1_89-1

Download citation

  • DOI: https://doi.org/10.1007/978-94-007-7864-1_89-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Dordrecht

  • Online ISBN: 978-94-007-7864-1

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

Publish with us

Policies and ethics

Search

Navigation