Synonyms
Definition
Personalized medicine is defined as the application of the right treatment for the right patient, at the right dose and at the right time. Personalized medicine is therefore a model of the way medicine will evolve through the use of specific treatments and therapies best suited to an individual’s genotype and is driven by patient demand for safer and more effective medicines and therapies.
Characteristics
The concept of individualizing treatment is not new, and the study of hereditary influences on the response to drugs (pharmacogenetics) is reflected in the scientific literature from the 1960s. The number of articles published remained constant until 1996 when technical developments and new insights into the highly complex nature of many diseases resulted in the advent of pharmacogenomics. Pharmacogenomics is closely related to pharmacogenetics, but the emphasis is on the influence of a whole set or complement of genes on the response to...
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References
Collins I, Workman P (2006) New approaches to molecular cancer therapeutics. Nat Chem Biol 2:689–700
Dietel M, Sers C (2006) Personalized medicine and development of targeted therapies: the upcoming challenge for diagnostic molecular pathology. A review. Virchows Arch 448:744–755
Powis G (2006) Achieving personalized cancer medicine: trials and tribulations. J Invest Med 54:235–237
Sikora K (2007) Personalized medicine for cancer: from molecular signature to therapeutic choice. Adv Cancer Res 96:345–369
See Also
(2012) Avastin. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 323. doi: 10.1007/978-3-642-16483-5_6577
(2012) Bioinformatics. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, pp 403–404. doi: 10.1007/978-3-642-16483-5_631
(2012) Biomarkers. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, pp 408–409. doi: 10.1007/978-3-642-16483-5_6601
(2012) Biopsy. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 415. doi: 10.1007/978-3-642-16483-5_644
(2012) FISH. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, pp 1415–1416. doi: 10.1007/978-3-642-16483-5_2197
(2012) EGFR. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1211. doi: 10.1007/978-3-642-16483-5_1828
(2012) Germline Mutation. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1544. doi: 10.1007/978-3-642-16483-5_2404
(2012) GIST. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1548. doi: 10.1007/978-3-642-16483-5_2411
(2012) Growth Factor. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, pp 1607–1608. doi: 10.1007/978-3-642-16483-5_2520
(2012) KIT. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, pp 1945–1946. doi: 10.1007/978-3-642-16483-5_3228
(2012) MYCN. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, pp 2430–2431. doi: 10.1007/978-3-642-16483-5_3925
(2012) Panitumumab. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2779. doi: 10.1007/978-3-642-16483-5_4362
(2012) Personalized Medicine. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2828. doi: 10.1007/978-3-642-16483-5_4476
(2012) Pharmacogenetics. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2840. doi: 10.1007/978-3-642-16483-5_4496
(2012) Pharmacogenotype. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2844. doi: 10.1007/978-3-642-16483-5_4498
(2012) Pharmacokinetics. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2845. doi: 10.1007/978-3-642-16483-5_4500
(2012) Phenomics. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2855. doi: 10.1007/978-3-642-16483-5_4513
(2012) Polymorphism. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, pp 2954–2955. doi: 10.1007/978-3-642-16483-5_4673
(2012) Targeted Therapy. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 3610. doi: 10.1007/978-3-642-16483-5_5677
(2012) Transcription. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 3752. doi: 10.1007/978-3-642-16483-5_5899
(2012) Wild-type. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 3947. doi: 10.1007/978-3-642-16483-5_6247
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Welsh, S.J., Powis, G. (2014). Personalized Cancer Medicine. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_4475-11
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DOI: https://doi.org/10.1007/978-3-642-27841-9_4475-11
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