Definition
The anaphase is a phase of mitosis, during which the paired sister-chromatids (Sister-chromatids) are separated and drawn to the poles of the cell. This phase is initiated by a ubiquitin-mediated proteolytic pathway (Ubiquitination) resulting in the degradation of regulatory proteins. The anaphase-promoting complex (APC/C) functions as a protein ubiquitin ligase.
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© 2011 Springer-Verlag Berlin Heidelberg
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(2011). Anaphase-Promoting Complex. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-16483-5_253
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DOI: https://doi.org/10.1007/978-3-642-16483-5_253
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Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-16482-8
Online ISBN: 978-3-642-16483-5
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