Keywords
Autocatalysis, cross-catalysis, informational molecule
Overview
Self-replication occurs when an informational molecule (such as a nucleic acid) directs the spontaneous synthesis of a replica of itself. Mechanisms for self-replication can be autocatalytic, where a molecule acts as a template to make a direct copy of itself, or cross-catalytic, where two or more molecules of different informational content amplify one another. Modern life forms use a complex cross-catalytic mechanism of replication that involves the participation of protein molecules that catalyze the replication of the informational polymer (nucleic acids), which are also involved in the synthesis of the catalysts themselves. Primordial life, however, could have...
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References and Further Reading
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Lee DH, Granja JR, Martinez JA, Severin K, Ghadiri MR (1996) A self-replicating peptide. Nature 382:525
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Orgel LE (1992) Molecular replication. Nature 358:203
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Ricardo, A. (2011). Self-Replication (Chemical). In: Gargaud, M., et al. Encyclopedia of Astrobiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11274-4_1423
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