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Detergents

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Kanerva’s Occupational Dermatology

Abstract

Household, personal, and industrial products contain detergents which play an important role in everyday life.

The term “detergency” is used to describe the process of cleaning by a surface-active agent (surfactant).

The most important ingredients of detergents are surfactants which display surface-tension-lowering properties so water can expand to wet surface, increasing washing effectiveness. Chemically, surfactants are amphiphilic molecules with a lipophilic tail and a hydrophilic head. They are categorized into four primary groups according to the charge present in the hydrophilic head: anionic, cationic, amphoteric, and nonionic. In the current market of cleaners and cleansers, anionic surfactants are the most common ones.

Surfactants may be irritating to the skin. The order of irritant potential of surfactants is the following: cationic = anionic > amphoteric > nonionic; however, mixtures of surfactants may elicit unexpected reactions.

Considering the widespread use and applications of household and personal detergents, the frequency of side effects to the skin is relatively low in an occupational as well in a personal exposure.

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References

  • Abbas S, Goldberg JW, Massaro M (2004) Personal cleanser technology and clinical performance. Dermatol Ther Suppl 1:35–42

    Article  Google Scholar 

  • Ananthapadmanabhan KP, Moore DJ, Subramanyan K, Misra M, Meyer F (2004) Cleansing without compromise: the impact of cleansers on the skin barrier and the technology of mild cleansing. Dermatol Ther Suppl 1:16–25

    Article  Google Scholar 

  • Andersen PH, Bindslev-Jensen C, Mosbech H, Zachariae H, Andersen KE (1998) Skin symptoms in patients with atopic dermatitis using enzyme-containing detergents. A placebo-controlled study. Acta Derm Venereol 78:60–62

    Article  CAS  PubMed  Google Scholar 

  • Austoria AJ, Lakshmi C, Srinivas CR, Anand CV, Mathew AC (2010) Irritancy potential of 17 detergents used commonly by the Indian household. Indian J Dermatol Venereol Leprol 76:249–253

    Article  CAS  PubMed  Google Scholar 

  • Bajpai D, Tyagi VK (2007) Laundry detergents: an overview. J Oleo Sci 56:327–340

    Article  CAS  PubMed  Google Scholar 

  • Basketter DA, English JS, Wakelin SH, White IR (2008) Enzymes, detergents and skin: facts and fantasies. Br J Dermatol 158:1177–1181

    Article  CAS  PubMed  Google Scholar 

  • Basketter DA, Pons-Guiraud A, van Asten A, Laverdet C, Marty JP, Martin L, Berthod D, Siest S, Giordano-Labadie F, Tennstedt D, Baeck M, Vigan M, Lainé G, Le Coz CJ, Jacobs MC, Bayrou O, Germaux MA (2010) Fragrance allergy: assessing the safety of washed fabrics. Contact Dermatitis 62:349–354

    Article  CAS  PubMed  Google Scholar 

  • Belsito DV, Fransway AF, Fowler JF Jr, Sherertz EF, Maibach HI, Mark JG Jr, Mathias CG, Rietschel RL, Storrs FJ, Nethercott JR (2002) Allergic contact dermatitis to detergents: a multicenter study to assess prevalence. J Am Acad Dermatol 46:200–206

    Article  PubMed  Google Scholar 

  • Corazza M, Lauriola MM, Zappaterra M, Bianchi A, Virgili A (2010) Surfactants, skin cleansing protagonists. J Eur Acad Dermatol Venereol 24:1–6

    Article  CAS  PubMed  Google Scholar 

  • Corea NV, Basketter DA, Clapp C, Van Asten A, Marty JP, Pons-Guiraud A, Laverdet C (2006) Fragrance allergy: assessing the risk from washed fabrics. Contact Dermatitis 55:48–53

    Article  CAS  PubMed  Google Scholar 

  • Effendy I, Maibach HI (1995) Surfactants and experimental irritant contact dermatitis. Contact Dermatitis 33:217–225

    Article  CAS  PubMed  Google Scholar 

  • Ertel K (2000) Modern skin cleansers. Dermatol Clin 18:561–575

    Article  CAS  PubMed  Google Scholar 

  • European Commission (1999) Scientific committee on cosmetic products and non-food products intended for consumers. Opinion concerning fragrance allergy in consumers. http://ec.europa.eu/health/ph_risk/committees/sccp/documents/out98_en.pdf. Accessed 12 Dec 2010

  • Fartasch M, Diepgen TL, Drexler H, Elsner P, Fluhr JW, John SM, Kresken J, Wigger-Alberti W (2011) Berufliche Hautmittel. http://www.derma.de/fileadmin/derma/pdfs/ll_berufliche_hautmittel.pdf. Accessed Feb 2011

  • Fluhr JW, Elias PM (2002) Stratum corneum pH: formation and function of the acid mantle. Exog Dermatol 1:163–175

    Article  CAS  Google Scholar 

  • Fowler JF Jr (2004) Cocamidopropyl betaine. Dermatitis 15:3–4

    Article  PubMed  Google Scholar 

  • Lodén M, Buraczewska I, Edlund F (2003) The irritation potential and reservoir effect of mild soaps. Contact Dermatitis 49:91–96

    Article  PubMed  Google Scholar 

  • Löffler H, Happle R (2003) Profile of irritant patch testing with detergents: sodium lauryl sulfate, sodium laureth sulfate and alkyl polyglucoside. Contact Dermatitis 48(2):6–32

    Google Scholar 

  • Magnano M, Silvani S, Vincenzi C, Nino M, Tosti A (2009) Contact allergens and irritants in household washing and cleaning products. Contact Dermatitis 61:337–341

    Article  CAS  PubMed  Google Scholar 

  • Matthies W, Löhr A, Ippen H (1990) Importance of detergent residues from the dermatoxicological point of view. Derm Beruf Umwelt 36:184–189

    Google Scholar 

  • Pepys J, Mitchell J, Hawkins R, Malo JL (1985) A longitudinal study of possible allergy to enzyme detergents. Clin Allergy 15:101–115

    Article  CAS  PubMed  Google Scholar 

  • Regulation (EC) No 648/2004 of the European Parliament and of the Council of 31 March 2004 on detergents. http://eur-lex.europa.eu/legal-content/EN/TXT/?uri=URISERV%3Al32025. Accessed 11 June 2017

  • Regulation (EU) No 259/2012 of the European Parliament and of the Council of 14 March 2012. http://eur-lex.europa.eu/legal-content/en/TXT/PDF/?uri=CELEX:02004R0648-20150601&from=EN. Assessed 11 June 2017

  • Schweigert MK, Mackenzie DP, Sarlo K (2000) Occupational asthma and allergy associated with the use of enzymes in the detergent industry–a review of the epidemiology, toxicology and methods of prevention. Clin Exp Allergy 30:1511–1518

    Article  CAS  PubMed  Google Scholar 

  • Terhaer FK, Bock M, Fartasch M, Gabard B, Elsner P, Kleesz P, Landeck L, Pohrt U, Seyfarth F, Schliemann S, Diepgen TL, Zagrodnik F, John SM (2010) Safety, effectiveness and comparability of professional skin cleansers. J Dtsch Dermatol Ges 8:806–810

    PubMed  Google Scholar 

  • The Council of the European Communities: Council Directive 76/768/EEC of 27 July 1976 on the approximation of the laws of the Member States relating to cosmetic products. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=CELEX:31976L0768:EN:HTML. Accessed 21 Dec 2010

  • The Soap and Detergent Association of Canada (2010) http://www.healthycleaning101.org/english/SDAC_soaps.html#his. Accessed 21 Dec 2010

  • Wagner G (2010) Waschmittel. Wiley-VCH, Weinheim

    Book  Google Scholar 

  • White IR, Lewis J, El Alami A (1985) Possible adverse reactions to an enzyme-containing washing powder. Contact Dermatitis 13:175–179

    Article  CAS  PubMed  Google Scholar 

  • Yazar K, Johnsson S, Lind ML, Boman A, Lidén C (2011) Preservatives and fragrances in selected consumer-available cosmetics and detergents. Contact Dermatitis 64:265–272

    Article  CAS  PubMed  Google Scholar 

  • Zug KA, Warshaw EM, Fowler JF Jr, Maibach HI, Belsito DL, Pratt MD, Sasseville D, Storrs FJ, Taylor JS, Mathias CG, Deleo VA, Rietschel RL, Marks J (2009) Patch-test results of the north American contact dermatitis group 2005–2006. Dermatitis 20:149–160

    PubMed  CAS  Google Scholar 

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Correspondence to Lilla Landeck .

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Landeck, L., Baden, L.A., John, SM. (2018). Detergents. In: John, S., Johansen, J., Rustemeyer, T., Elsner, P., Maibach, H. (eds) Kanerva’s Occupational Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-40221-5_75-2

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  • DOI: https://doi.org/10.1007/978-3-319-40221-5_75-2

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  • Print ISBN: 978-3-319-40221-5

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