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Handbook of Macrocyclic Supramolecular Assembly

  • Living reference work
  • © 2020


  • Discusses the key issues in supramolecular assembly, from building blocks to well-organized architectures
  • Provides comprehensive information, from historic reviews to the latest results
  • Offers an update on the new applications of supramolecular assembly with biological functions

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About this book

This handbook presents recent advances and offers a comprehensive reference resource covering the developments in and applications of macrocyclic supramolecular assembly, with a focus on their construction, structural characters and biological functions. The main topics addressed include: 

  1. Construction and structure of macrocyclic supramolecular assembly – key building blocks, construction methods, structural motifs, and stimuli responsive control
  2. Approach and technology – controllable synthesis, molecular recognition, spectral and thermodynamic study, supramolecular assembly at interfaces, orthogonal self-assembly, the supramolecular organic framwork (SOF), molecular induced aggregation, supramolecule assisted 3D printing, theoretical calculation and molecular simulation 
  3. Biological applications – chemical and biological sensing, theranostic tools, molecule/ion channels, drug/gene delivery, supramolecule assisted biomolecule production, supramolecule assisted transmembrane transport, supramolecule assisted immunity regulation, supramolecule-based medicinal drug, etc. 
This handbook appeals to graduate and undergraduate students as well as scientists with interests in supramolecular chemistry, biochemistry, functional material and nanotechnology.

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Table of contents (59 entries)

Editors and Affiliations

  • College of Chemistry, Nankai University College of Chemistry, Tianjin, China

    Yu Liu, Yong Chen, Heng-Yi Zhang

About the editors

Prof. Dr. Yu Liu, born in 1954, is a professor at Nankai University. He received his PhD from Himeji Institute of Technology, Japan, in 1991, and then spent two years (1991-1992) as a postdoctoral fellow at Lanzhou Institute of Chemical Physics. In 1993, he moved to Nankai University as a professor and received the Special government allowances of the State Council. He obtained National Outstanding Youth Fund support in 1996, and is now the specially appointed professor of Cheung Kong Scholars Programme. He has made significant contributions in the field of supramolecular chemistry of crown ether, cyclodextrin and calixarene, written over 400 articles and contributed to eight books. He won a Chinese Academy of Science second class Award of Natural Science of in 1990, a Ministry of Education second class Award for Scientific and Technological Progress of in 1998, Tianjin first class Awards of Natural Science in 2000 and 2005, respectively, a Ministry of Education second class Award of Natural Science in 2002, and a Baogang special grade Award of Outstanding Teacher in 2003.

Prof. Dr. Yong Chen obtained his PhD degree in 2001 at Nankai University (China), majoring in physical organic chemistry based on cyclodextrins. After one year's research as an assistant professor at the Institute of Chemistry, Chinese Academy of Science, he moved to Ecole Normale Superieure (ENS, France) as a postdoc at the invitation of the National Scientific Research Center of France (CNRS). At the end of 2003, Dr. Yong Chen joined the Supramolecular Chemistry Laboratory of Nankai University as an associated professor, and became a professor in 2009.

Prof. Dr. Heng-Yi Zhang was born in 1965 in Wuwei, Anhui Province, and received his PhD in 2000 from Nankai University, where he became a lecturer soon afterwards. He became an associated professor in 2001, and a professor in 2006. He obtained support from the Program for New Century Excellent Talents in University in 2005. Hisinterests are focused on physical organic chemistry and supramolecular chemistry. He has contributed to four books and more than 80 articles. He won a Ministry of Education second class Award of Natural Science in 2002, and a Tianjin first class Award of Natural Science in 2005.

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