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Table of contents

  1. Front Matter
    Pages i-xxv
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Roland Stockmann
      Pages 25-59
  3. Envenomation

    1. Front Matter
      Pages 61-61
    2. Fatima Laraba-Djebari, Sonia Adi-Bessalem, Djelila Hammoudi-Triki
      Pages 63-85
    3. Sonia Adi-Bessalem, Djelila Hammoudi-Triki, Fatima Laraba-Djebari
      Pages 87-107
    4. Carlos Sevcik, Gina D’Suze
      Pages 109-136
  4. Antivenoms

    1. Front Matter
      Pages 137-137
    2. Everardo Remi Rodríguez Rodríguez, Lidia Riaño Umbarila, Lourival D. Possani, Baltazar Becerril
      Pages 139-159
    3. Aurora Alvarez, Yuyibeth Montero, Pedro Parrilla, Caridad Malave, Noraida Zerpa
      Pages 161-178
  5. Scorpionism

    1. Front Matter
      Pages 179-179
    2. Zuhair Sami Amr
      Pages 181-200
    3. Alfredo Luis Chávez-Haro, Ernesto Ortiz
      Pages 201-213
    4. Jimmy Alexander Guerrero-Vargas, Javier Roberto Rodríguez Buitrago, Santiago Ayerbe, Eduardo Flórez Daza, José Toribio Beltrán Vidal
      Pages 245-272
    5. Gina D’Suze, Cecilia Castillo, Carlos Sevcik, Josmary Brazón, Caridad Malave, Deyanell Hernandez et al.
      Pages 273-298
    6. Manuela Berto Pucca, Fagner Neves Oliveira, Elisabeth F. Schwartz, Eliane Candiani Arantes, Rejâne Maria Lira-da-Silva
      Pages 299-324
  6. Scorpion Venoms

    1. Front Matter
      Pages 325-325
    2. Antony Gomes, Aparna Gomes
      Pages 351-367
    3. Peter N. Strong, Sandeepan Mukherjee, Nakul Shah, Abhay Chowdhary, Kandiah Jeyaseelan
      Pages 369-382
    4. Karla de Castro Figueiredo Bordon, Camila Takeno Cologna, Eliane Candiani Arantes
      Pages 411-437
  7. Scorpion Toxins

    1. Front Matter
      Pages 439-439
    2. Marie-France Martin-Eauclaire, Najwa Abbas, Brigitte Céard, Jean-Pierre Rosso, Pierre E. Bougis
      Pages 441-469
    3. Michael Gurevitz, Dalia Gordon, Maya Gur Barzilai, Roy Kahn, Lior Cohen, Yehu Moran et al.
      Pages 471-491
    4. Adam Bartok, Gyorgy Panyi, Zoltan Varga
      Pages 493-527
  8. Venomics

    1. Front Matter
      Pages 529-529
    2. Martha Rendón-Anaya, Thalita S. Camargos, Ernesto Ortiz
      Pages 531-545
    3. Jennifer J. Smith, Paul F. Alewood
      Pages 547-561
  9. Back Matter
    Pages 563-575

About this book

Introduction

Scorpions have fascinated humans for a long time, first and foremost because of the harm the sting of a few species could cause but also due to their unique natural history and for the many biologically active compounds found in their venoms. This volume of the Toxinology handbook series covers all those aspects. The subjects are divided into seven sections starting with an introduction to the general aspects of scorpion biology and ecology, followed by the description of the “envenomation” pathophysiology, pharmacokinetics, and pharmacodynamics of venoms and their complex interactions with the immune system. The future of anti-scorpion venom therapy is then covered in two chapters dedicated to alternatives to the century-old techniques currently used to produce “anti-venoms”. The next section presents a world tour of “scorpionism” and dangerous scorpion species and their impact on human health. It is worth remembering that envenomation due to scorpion stings is a substantial health hazard in Asian, Middle Eastern, African, and Latin American countries, with over one million people stung by scorpions every year, resulting in more than 3,000 deaths. Species-centered overviews of “scorpion venoms” are presented in the next section, after which a section details the two main types of “scorpion toxins”. The last section covers high-throughput transcriptome and proteome screenings now known as “venomics”.

 

This volume provides chapters that are accessible to a broad audience, yet also contains the depth of knowledge and detail which makes it of interest to experts in the field. Readers of this reference work will leave well informed on the current state of the art of scorpion venom research.

Keywords

Drug Development Drug Discovery Toxin Toxinology Venom

Editors and affiliations

  • P. Gopalakrishnakone
    • 1
  • Lourival D. Possani
    • 2
  • Elisabeth F. Schwartz
    • 3
  • Ricardo C. Rodríguez de la Vega
    • 4
  1. 1.Venom and Toxin Research Programme Department of AnatomyYong Loo Lin School of Medicine National University of SingaporeSingaporeSingapore
  2. 2.Departamento de Medicina Molecular y BioprocesosInstituto de Biotecnologı´a Universidad Nacional Autonoma de Mexico (UNAM)CuernavacaMexico
  3. 3.Departamento de Ciências Fisiológicas -Universidade de Brasília Laboratório de ToxinologiaBrasilia, DFBrazil
  4. 4.Laboratoire Ecologie, Systématique et Evolution Université Paris-Sud, CNRSORSAYFrance

Bibliographic information