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  • Reference work
  • © 2017

Textbook of Aging Skin


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  • Describes recent advances in scientific, medical and technical understanding of the aging skin

  • Covers all aspects, from basic science to diseases, techniques, toxicology and psychosocial issues

  • Explores global perspectives, including perception, needs and responses to skin aging

  • Brings the reader up to date with many completely new chapters

  • Includes supplementary material:

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USD 1,199.99
Price excludes VAT (USA)
  • ISBN: 978-3-662-47398-6
  • Instant PDF download
  • Readable on all devices
  • Own it forever
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  • Tax calculation will be finalised during checkout
Hardcover Book
USD 1,599.99
Price excludes VAT (USA)

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Table of contents (161 entries)

  1. Front Matter

    Pages i-xlvii
  2. Basic Sciences/Physiology/Histology

    1. Front Matter

      Pages 1-1
    2. Degenerative Changes in Aging Skin

      • Miranda A. Farage, Kenneth W. Miller, Howard I. Maibach
      Pages 15-30
    3. Skin Aging: A Brief Summary of Characteristic Changes

      • Cornelia Wiegand, Christina Raschke, Peter Elsner
      Pages 55-65
    4. The Stratum Corneum and Aging

      • Anthony V. Rawlings
      Pages 67-90
    5. The Extracellular Matrix Protein 1 (ECM1) in Molecular-Based Skin Biology

      • Noritaka Oyama, Joseph Merregaert
      Pages 91-110
    6. Pathomechanisms of Endogenously Aged Skin

      • Evgenia Makrantonaki, Christos C. Zouboulis
      Pages 111-120
    7. Pathomechanisms of Photoaged Skin

      • Jean Krutmann
      Pages 121-129
    8. Proteoglycans in Skin Aging

      • François-Xavier Maquart, Stéphane Brézillon, Yanusz Wegrowski
      Pages 131-147
    9. Buffering Capacity Considerations in the Elderly

      • Jacquelyn Levin, Howard I. Maibach
      Pages 161-172
    10. Aging of Epidermal Stem Cells

      • Alexandra Charruyer, Ruby Ghadially
      Pages 191-204
    11. Peroxisome Proliferator-Activated Receptors: Role in Skin Health and Appearance of Photoaged Skin

      • Stacy S. Hawkins, William Shingleton, Jean Adamus, Helen Meldrum
      Pages 225-238
    12. Hyaluronan and the Process of Aging in Skin

      • Diana Alyce Rivers, Robert Stern
      Pages 239-254

About this book

This comprehensive book presents the latest information on all aspects of the aging skin, including a broad spectrum of the relevant basic science, malignant and non-malignant age-associated diseases and conditions, techniques and methods, toxicological and safety considerations in the elderly, psychological and social issues, ethnicity and gender differences and marketing to the aged. Since the first edition the book has been extensively updated and revised, with the inclusion of many additional chapters that describe the most recent advances in scientific, medical and technical understanding of the aging phenomenon. There is, for example, extended coverage of physiology, description of novel bioengineering methods and tools, detailed consideration of developments in genomics research, and information on new ingredients and products. Textbook of Aging Skin is written by global experts and thought leaders and is intended to serve as the single and complete reference on the subject. It will be of value for dermatologists, gerontologists, toxicologists, biologists and a range of other professionals.


  • Anti-aging strategies
  • Bioengineering
  • Cosmetic surgery
  • Malignant and non-malignant skin conditions
  • Skin damage

Editors and Affiliations

  • Winton Hill Business Center, The Procter & Gamble Company , Cincinnati, USA

    Miranda A. Farage

  • Margoshes-Miller Consulting, LLC, Cincinnati, USA

    Kenneth W. Miller

  • Department of Dermatology, University of California, San Francisco, USA

    Howard I. Maibach

About the editors

Miranda A. Farage is a Research Fellow in the Global Clinical Sciences Innovation at the Procter & Gamble Company, Cincinnati, Ohio. Dr. Farage leads global research on genital health, dermatological testing and claims, new clinical methods development, sensitive skin, physiology, clinical toxicology, women’s health, quality of life, and related fields. Dr. Farage has invented novel state-of-the-art clinical test methods that have resulted in efficient ways of assessing new technologies and products as well as the filing of 15 patent applications. She has published more than 200 manuscripts and chapters in peer-reviewed journals and medical books. She is the Editor-in-Chief of several books such as The Vulva; Textbook of Aging Skin, first edition; Topical Application and the Mucosa; and Skin, Mucosa and Menopause: Management of Clinical Issues. Dr. Farage is a member of many scientific societies including the American Academy of Dermatology, the European College of Society of Vulva Diseases, the National Vulvodynia Association, the American Society for Testing and Materials (ASTM) International, and the Science Advisory Board. Currently, she is serving on the editorial boards of more than a dozen scientific, dermatology, and medical journals. She received a Ph.D. in Medical Sciences and a master degree (MS) in Biology from the University of Illinois, Urbana-Champaign. Before joining Procter & Gamble, she was a faculty member at the Virginia Polytechnic Institute and State University (Virginia Tech).

Dr. Kenneth Miller is Principle Consultant for Product Safety, Toxicology, and Regulatory Strategy at Margoshes Miller Consulting LLC. He is also the Associate Director for Global Product Safety, Regulatory and Microbiology in for the Feminine Care and Family Care business units at The Procter and Gamble Company. Dr. Miller is responsible for the strategic development and execution of research and testing in the areas of dermatoxicology, clinical safety and efficacy studies, post-market surveillance studies, epidemiology studies, environmental studies (biodegradation, solid waste disposal, aquatic and terrestrial toxicology and global waste disposal infrastructure), standard microbiological testing and microbiological methods development research (including molecular microbiology techniques). Too, he has responsibility for a team conducting microbiological and clinical research in toxic shock syndrome, superantigens, and vaginal microbial ecology. Dr. Miller has published over twenty-five manuscripts in the area of toxicology in peer-reviewed journals plus numerous abstracts and presentations at meetings of scientific societies. Dr. Miller is board-certified in toxicology (DABT) and a member of several scientific and professional societies.

Dr. Howard Maibach joined the University of California Faculty as Assistant Professor and is currently Professor of Dermatology. Dr. Maibach, an expert in contact and occupational dermatitis, sees patients at the Environmental Dermatoses Clinic, which is part of the Dermatology Clinic at UCSF. His most active fields of research are in dermatopharmacology, dermatotoxicology, and environmental dermatoses. He has been doing human subject research for 45 years. He has been on the editorial board of more than 30 scientific journals. His bibliography includes more than 2790 publications and 100 books. He is member of 19 professional societies including the American Academy of Dermatology (AAD), San Francisco Dermatological Society (SFDS), North American Contact Dermatitis Group (NACDG), American Contact Dermatitis Society (ACDS), International Contact Dermatitis Research Group (ICDRG), Society of Toxicology (SOT), European Environmental and Contact Dermatitis Research Group (EECDRG), and the Internal Commission on Occupational Health. He is a consultant to government, academia, and industry worldwide. Dr. Howard Maibach was honored as the 2013 recipient of The Master Dermatologist Award by The American Academy of Dermatology’s 71st Annual Conference held in Miami, Florida. This prestigious award recognizes an Academy member’s significant contributions to the field of dermatology and to the American Academy of Dermatology. About the Editors xxix In March 2015, The International League of Dermatological Societies (ILDS) awarded Dr. Maibach their 2014 ILDS Certificate of Appreciation in recognition of his outstanding contribution to dermatology, both nationally and internationally, through his work, research, publications, and teaching in the USA and over 60 countries.

Bibliographic Information

  • Book Title: Textbook of Aging Skin

  • Editors: Miranda A. Farage, Kenneth W. Miller, Howard I. Maibach

  • DOI:

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Reference Module Medicine

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2017

  • Hardcover ISBN: 978-3-662-47397-9

  • Edition Number: 2

  • Number of Pages: XLVII, 2222

  • Number of Illustrations: 149 b/w illustrations, 424 illustrations in colour

  • Topics: Dermatology, Geriatrics, Gynecology

Buying options

USD 1,199.99
Price excludes VAT (USA)
  • ISBN: 978-3-662-47398-6
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Hardcover Book
USD 1,599.99
Price excludes VAT (USA)