Table of contents

  1. Front Matter
    Pages 1-61
  2. General Topics

    1. Front Matter
      Pages 1-1
    2. Zdeňka Ďuračková
      Pages 3-38
    3. Pat Monaghan, David Costantini
      Pages 39-64
    4. Frazer Lowe
      Pages 65-87
    5. Simon V. Avery
      Pages 89-112
    6. Neelam Azad, Anand Krishnan V. Iyer
      Pages 113-135
    7. Anna Csiszar, Zoltan Ungvari
      Pages 137-151
    8. Adam B. Salmon, Arlan Richardson, Viviana I. Pérez
      Pages 153-170
    9. Joanne Kilgour, Ruth Roberts
      Pages 171-206
    10. Gnanapragasam Arunachalam, Samson Mathews Samuel, Hong Ding, Chris R. Triggle
      Pages 207-242
    11. Xianhua Wang, Qi Ma, Wang Wang, Heping Cheng
      Pages 243-263
    12. Lucie Duluc, Ramaroson Andriantsitohaina, Gilles Simard
      Pages 279-293
    13. R. A. Zinovkin, L. E. Bakeeva, B. V. Chernyak, M. V. Egorov, N. K. Isaev, N. G. Kolosova et al.
      Pages 323-354
    14. Hamid I. Akbarali
      Pages 355-373
    15. Duško P. Blagojević
      Pages 375-391
    16. Zsolt Radak, Zoltan Acs, Zoltan Bori, Albert W. Taylor, Hu Yang
      Pages 407-416

About this book


The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants. Free radical induced cellular damage in a variety of tissues and organs is reviewed, with detailed discussion of molecular and cellular mechanisms. The collection is aimed at those new to the field, as well as clinicians and scientists with long standing interests in free radical biology. A feature of this collection is that the material also brings insights into various diseases where free radicals are thought to play a role. There is extensive discussion of the success and limitations of the use of antioxidants in several clinical settings.


RNS ROS Systems biology anti-oxidants disease free radicals organ oxidative stress

Editors and affiliations

  • Ismail Laher
    • 1
  1. 1.Department of Pharmacology and TherapeuticsUniversity of British ColombiaVancouverCanada

About the editors

Ismail (Issy) Laher, Ph.D., is a Professor at the Department of Pharmacology and Therapeutics at the Faculty of Medicine of the University of British Columbia in Vancouver,Canada. He is also a Visiting Professor at the Department of Pharmacology at the University of Vermont, USA.  Trained at the University of London in pharmacology, he then continued with additional training in cardiovascular pharmacology at UBC and UVM, with a focus on the regulation of resistance artery regulation in health and disease.

Bibliographic information