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Table of contents

  1. Front Matter
    Pages I-LVIII
  2. Hans Gerhard Vogel
    Pages 47-391
  3. Hans Gerhard Vogel
    Pages 393-455
  4. Hans Gerhard Vogel
    Pages 457-510
  5. Hans Gerhard Vogel
    Pages 511-564
  6. Hans Gerhard Vogel
    Pages 565-876
  7. Hans Gerhard Vogel
    Pages 877-942
  8. Hans Gerhard Vogel
    Pages 943-981
  9. Hans Gerhard Vogel
    Pages 1117-1190
  10. Hans Gerhard Vogel
    Pages 1191-1321
  11. Hans Gerhard Vogel
    Pages 1323-1607
  12. Hans Gerhard Vogel
    Pages 1609-1660
  13. Hans Gerhard Vogel
    Pages 1661-1717
  14. Hans Gerhard Vogel
    Pages 1719-1916
  15. Hans Gerhard Vogel
    Pages 1917-1939
  16. Hans Gerhard Vogel
    Pages 1941-2021
  17. Hans Gerhard Vogel
    Pages 2023-2037
  18. Back Matter
    Pages 2039-2071

About this book

Introduction

The rapid progress in biology will continue to change the methodological approach to drug discovery in the coming years. Electronic media will continuously help researchers to access and share information. It is, however, becoming more and more evident that many young pharmacologists have only limited training in classical pharmacological methodologies. These long-standing and still highly relevant methods are simply not available in the electronic databases. Drug Discovery and Evaluation:Pharmacological Assays bridges this gap by comprehensively covering the pharmacological methods that have been utilized successfully for more than a hundred years as well as the latest technologies.

The classical methods and the newest technologies, all in one book!

The 3rd edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal, and immunomodulatory activities. Each of the more than 1000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. In addition, animal models of rare diseases are described.

For this third edition, all existing chapters have been revised and completely updated. A large number of assays were added: we are now publishing two volumes. Sections that have been specifically enlarged include - Pharmacological assays in thrombosis and haemostasis (formerly called activity of blood constituents), - Antidiabetic activity (includes completely new chapters such as Biochemical Methods in Diabetology), - Anti-atherosclerotic activity.

Audience: Pharmacologists and Pharmacists in Academia and Industry

Keywords

Arzneimittel Arzneimittelwirkungen Pharmakologie Toxikologie Wirkstoffe Wirkstoffforschung assays drug action drugs pharmacological tests toxicology

Editors and affiliations

  • Hans Gerhard Vogel
    • 1
  1. 1.AalenGermany

Bibliographic information