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Table of contents

  1. Massimo Cuzzolaro
  2. R. Drew Sayer, James O. Hill
  3. Lyn D. Ferguson, Naveed Sattar
  4. Antonio Giordano, Enzo Nisoli
  5. Paul Cordero, Jiawei Li, Jude A. Oben
  6. Ian W. Seetho, John P.H. Wilding
  7. Sviatlana Zhyzhneuskaya, Roy Taylor
  8. Claudia K. Fox, Justin R. Ryder, Amy C. Gross, Aaron S. Kelly
  9. Roberto Vettor, Scilla Conci
  10. Vasilios Kotsis, Christina Antza, Giannis Doundoulakis, Stella Stabouli
  11. Lidia Castagneto Gissey, James Casella Mariolo, Geltrude Mingrone
  12. Phong Ching Lee, John B. Dixon
  13. Saverio Cinti
  14. Gemma Xifra, José Maria Moreno-Navarrete, José Manuel Fernández-Real

About this book

Introduction

This book presents the latest advances in our understanding of the pathophysiologic basis that induces the chronic positive energy balance necessary to progressively store excessive amounts of fat mass. It highlights the clinical complications of obesity, while also focusing on the major scientific advances that have highlighted the role of genetics, adipose tissue endocrinology and the environment in the mechanisms and causes of obesity. Particular attention is given to the consequences of obesity, including an ever -increasing number of other diseases such as type 2 diabetes, cardiovascular diseases and cancer, as well as conditions such as arthropathy, asthma, non-alcoholic liver disease, and dementia. Increasingly recognized uniting causes highlight the role of systemic, local and paracrine actions of adipocytokines in causing inflammation. As we come to better understand how hypothalamic control of energy balance is influenced by endocrine signaling from the gut and adipose tissue, it paves the way for new therapeutic targets and a resurgence of pharmacological and surgical approaches to treatment. 

Written by respected experts in the field, this volume is intended as a major reference source for endocrinologists, nutritionists, basic and clinical scientists alike.

Keywords

Neuroendocrinology of energy balance Adipose organ Eating disorders Dietary treatment Pharmacological approaches Surgical approaches

Editors and affiliations

  • Paolo Sbraccia
    • 1
  • Nicholas Finer
    • 2
  1. 1.Department of Systems Medicine, Internal Medicine Unit and Obesity CenterUniversity of Rome Tor Vergata, University Hospital Policlinico Tor VergataRomeItaly
  2. 2.UCL Institute of Cardiovascular ScienceNational Centre for Cardiovascular PreventionLondonUK

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-47685-8
  • Copyright Information Springer Nature Switzerland AG 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Online ISBN 978-3-319-47685-8
  • Series Print ISSN 2510-1927
  • Series Online ISSN 2510-1935