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  • Living reference work
  • © 2020


Biology, Technology, Therapy

  • Treats both theoretical and practical aspects of bacteriophage therapy

  • Provides complete instructions for the detection of bacteriophages

  • Covers bacteriophage biology from their structur and function to genetics

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Table of contents (41 entries)

  1. Adsorption: Phage Acquisition of Bacteria

    • John J. Dennehy, Stephen T. Abedon
  2. Bacteria-Phage Antagonistic Coevolution and the Implications for Phage Therapy

    • Michael A. Brockhurst, Britt Koskella, Quan-Guo Zhang
  3. Bacteriophage Ecology

    • John J. Dennehy, Stephen T. Abedon
  4. Bacteriophage Manufacturing: From Early Twentieth-Century Processes to Current GMP

    • Krzysztof Regulski, Patrick Champion-Arnaud, Jérôme Gabard
  5. Bacteriophage Pharmacology and Immunology

    • Krystyna Dąbrowska, Andrzej Górski, Stephen T. Abedon
  6. Bacteriophage Utilization in Animal Hygiene

    • Sarah Klopatek, Todd R. Callaway, Tryon Wickersham, T. G. Sheridan, D. J. Nisbet
  7. Biofilm Applications of Bacteriophages

    • Catarina Milho, Maria Daniela Silva, Sanna Sillankorva, D. R. Harper
  8. Clinical Trials of Bacteriophage Therapeutics

    • Shawna McCallin, Harald Brüssow
  9. Crop Use of Bacteriophages

    • Jeffrey B. Jones, Antonet M. Svircev, Aleksa Ž. Obradović
  10. Current Updates from the Long-Standing Phage Research Centers in Georgia, Poland, and Russia

    • Ryszard Międzybrodzki, Naomi Hoyle, Fikria Zhvaniya, Marzanna Łusiak-Szelachowska, Beata Weber-Dąbrowska, Małgorzata Łobocka et al.
  11. Detection of Bacteriophages: Sequence-Based Systems

    • Siân V. Owen, Blanca M. Perez-Sepulveda, Evelien M. Adriaenssens

About this book

The intention is to provide a defininitive reference work on the technological and therapeutic applications of bacteriophages. The main areas to be covered are indicated in the subtitles. It is intended to avoid an overdependence on reciting the history of the approach and rather to concentrate on its practical utility, albeit placing that in its appropriate context.


  • Bacteriophages
  • Host resistance
  • Phage infection
  • Biocontrol agents
  • Environmental Hygiene
  • antibiotic resistance

Editors and Affiliations

  • Evolution Biotechnologies, Milton Keynes, United Kingdom

    David R. Harper, Malcolm L. McConville

  • Dept. of Microbiology, The Ohio State University Dept. of Microbiology, Mansfield, USA

    Stephen T. Abedon

  • GeneWEAVE Biosciences, Roche Molecular Systems GeneWEAVE Biosciences, Los Gatos, USA

    Benjamin H. Burrowes

About the editors

Dr. David Harper has a scientific background in virology and microbiology is the Chief Officer of Evolution Biotechnologies. He was the founder, CEO and CSO of Biocontrol Limited and CSO of AmpliPhi Biosciences and managed the first modern regulated clinical trial to demonstrate the efficacy of bacteriophages. He is a member of the Alternatives to Antibiotics panel, a collaboration between the Wellcome Trust and the UK Department of Health.

Dr. Stephen Abedon has been a member of the faculty of the Ohio State University, Department of Microbiology, for over 20 years. He has been studying bacteriophages for 30-plus years and has approximately 100 phage-based publications including six monographs or equivalents on phages which he has edited (five) or authored (one), along with three more edited volumes currently in progress. Additional information and resources can be found at

Dr Ben Burrowes gained his PhD in Medical Microbiology from Texas Tech University Health Sciences Center in 2010, where his research focus was the development of therapeutic bacteriophages with extended host range using in vitro evolution. Upon leaving Texas, Dr Burrowes worked at Biocontrol Inc. (now AmpliPhi Biosciences Corporation) developing multiple human phage therapy preparations targeting several major bacterial pathogens. Since 2013 Dr Burrowes has worked for GeneWEAVE Biosciences (now a division of Roche Molecular Systems) assisting in the development of rapid diagnostics for drug resistant bacteria using a proprietary phage-based platform.

Bibliographic Information

  • Book Title: Bacteriophages

  • Book Subtitle: Biology, Technology, Therapy

  • Editors: David R. Harper, Stephen T. Abedon, Benjamin H. Burrowes, Malcolm L. McConville

  • DOI:

  • Publisher: Springer Cham

  • eBook Packages: Springer Reference Biomedicine & Life Sciences, Reference Module Biomedical and Life Sciences

  • Topics: Medical Genetics, Microbiology