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Bacteriophages

Biology, Technology, Therapy

  • David R. Harper
  • Stephen T. Abedon
  • Benjamin H. Burrowes
  • Malcolm L. McConville
  • Treats both theoretical and practical aspects of bacteriophage therapy

  • Provides complete instructions for the detection of bacteriophages

  • Covers bacteriophage biology from their structur and function to genetics

Living reference work

Table of contents

  1. John J. Dennehy, Stephen T. Abedon
  2. Michael A. Brockhurst, Britt Koskella, Quan-Guo Zhang
  3. John J. Dennehy, Stephen T. Abedon
  4. Krzysztof Regulski, Patrick Champion-Arnaud, Jérôme Gabard
  5. Krystyna Dąbrowska, Andrzej Górski, Stephen T. Abedon
  6. Sarah Klopatek, Todd R. Callaway, Tryon Wickersham, T. G. Sheridan, D. J. Nisbet
  7. Catarina Milho, Maria Daniela Silva, Sanna Sillankorva, D. R. Harper
  8. Shawna McCallin, Harald Brüssow
  9. Jeffrey B. Jones, Antonet M. Svircev, Aleksa Ž. Obradović
  10. Ryszard Międzybrodzki, Naomi Hoyle, Fikria Zhvaniya, Marzanna Łusiak-Szelachowska, Beata Weber-Dąbrowska, Małgorzata Łobocka et al.
  11. Siân V. Owen, Blanca M. Perez-Sepulveda, Evelien M. Adriaenssens

About this book

Introduction

The intention is to provide a defininitive reference work on the technological and therapeutic applications of bacteriophages. The main areas to be covered are indicated in the subtitles. It is intended to avoid an overdependence on reciting the history of the approach and rather to concentrate on its practical utility, albeit placing that in its appropriate context.

Keywords

Bacteriophages Host resistance Phage infection Biocontrol agents Environmental Hygiene antibiotic resistance

Editors and affiliations

  • David R. Harper
    • 1
  • Stephen T. Abedon
    • 2
  • Benjamin H. Burrowes
    • 3
  • Malcolm L. McConville
    • 4
  1. 1.Evolution BiotechnologiesMilton KeynesUnited Kingdom
  2. 2.Dept. of MicrobiologyThe Ohio State University Dept. of MicrobiologyMansfieldUSA
  3. 3.GeneWEAVE BiosciencesRoche Molecular Systems GeneWEAVE BiosciencesLos GatosUSA
  4. 4.Evolution BiotechnologiesMilton KeynesUnited Kingdom

About the editors

Dr. David Harper has a scientific background in virology and microbiology is the Chief Officer of Evolution Biotechnologies. He was the founder, CEO and CSO of Biocontrol Limited and CSO of AmpliPhi Biosciences and managed the first modern regulated clinical trial to demonstrate the efficacy of bacteriophages. He is a member of the Alternatives to Antibiotics panel, a collaboration between the Wellcome Trust and the UK Department of Health.

Dr. Stephen Abedon has been a member of the faculty of the Ohio State University, Department of Microbiology, for over 20 years. He has been studying bacteriophages for 30-plus years and has approximately 100 phage-based publications including six monographs or equivalents on phages which he has edited (five) or authored (one), along with three more edited volumes currently in progress. Additional information and resources can be found at abedon.phage.org.

Dr Ben Burrowes gained his PhD in Medical Microbiology from Texas Tech University Health Sciences Center in 2010, where his research focus was the development of therapeutic bacteriophages with extended host range using in vitro evolution. Upon leaving Texas, Dr Burrowes worked at Biocontrol Inc. (now AmpliPhi Biosciences Corporation) developing multiple human phage therapy preparations targeting several major bacterial pathogens. Since 2013 Dr Burrowes has worked for GeneWEAVE Biosciences (now a division of Roche Molecular Systems) assisting in the development of rapid diagnostics for drug resistant bacteria using a proprietary phage-based platform.


Bibliographic information

  • Book Title Bacteriophages
  • Book Subtitle Biology, Technology, Therapy
  • Editors David R. Harper
    Stephen T. Abedon
    Benjamin H. Burrowes
    Malcolm L. McConville
  • DOI https://doi.org/10.1007/978-3-319-40598-8
  • Publisher Name Springer, Cham
  • eBook Packages Springer Reference Biomedicine & Life Sciences Reference Module Biomedical and Life Sciences
  • eBook ISBN 978-3-319-40598-8
  • Edition Number 0
  • Number of Pages , 0
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Gene Therapy
    Bacteriology