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  • Reference work
  • © 2015

Optical Coherence Tomography

Technology and Applications


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  • Opens the latest developments in OCT to a broad readership, from undergraduates to experts

  • Presents the OCT technique from optical, technological, biomedical & clinical points of view

  • Incorporates work from top engineering and clinical groups, from research to application

  • Provides an accessible introduction to optical coherence tomography technology (OCT)

  • Includes supplementary material:

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  • ISBN: 978-3-319-06419-2
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Table of contents (84 entries)

  1. Front Matter

    Pages i-xxx
  2. Introduction to OCT

    1. Front Matter

      Pages 1-1
    2. Introduction to OCT

      • James G. Fujimoto, Wolfgang Drexler
      Pages 3-64
    3. Theory of Optical Coherence Tomography

      • Joseph A. Izatt, Michael A. Choma, Al-Hafeez Dhalla
      Pages 65-94
    4. Modeling Light–Tissue Interaction in Optical Coherence Tomography Systems

      • Peter E. Andersen, Thomas M. Jørgensen, Lars Thrane, Andreas Tycho, Harold T. Yura
      Pages 95-140
  3. OCT Technology

    1. Front Matter

      Pages 141-141
    2. Inverse Scattering and Aperture Synthesis in OCT

      • Adolf F. Fercher
      Pages 143-164
    3. Spectral/Fourier Domain Optical Coherence Tomography

      • Johannes F. de Boer
      Pages 165-193
    4. Complex and Coherence-Noise Free Fourier Domain Optical Coherence Tomography

      • Rainer A. Leitgeb, Maciej Wojtkowski
      Pages 195-224
    5. Optical Frequency Domain Imaging

      • Brett E. Bouma, Guillermo J. Tearney, Benjamin Vakoc, Seok Hyun Yun
      Pages 225-254
    6. Complex Conjugate Removal in SS Optical Coherence Tomography

      • Oscar Carrasco-Zevallos, Joseph A. Izatt
      Pages 255-276
    7. Ultrahigh Resolution Optical Coherence Tomography

      • Wolfgang Drexler, Yu Chen, Aaron D. Aguirre, Boris Považay, Angelika Unterhuber, James G. Fujimoto
      Pages 277-318
    8. Ultrahigh Speed OCT

      • Ireneusz Grulkowski, Jonathan J. Liu, Benjamin Potsaid, Vijaysekhar Jayaraman, Alex E. Cable, James G. Fujimoto
      Pages 319-356
    9. Optical Design for OCT

      • Zhilin Hu, Andrew M. Rollins
      Pages 357-384
    10. Linear OCT Systems

      • Gereon Hüttmann, Peter Koch, Reginald Birngruber
      Pages 385-406
    11. Data Analysis and Signal Postprocessing for Optical Coherence Tomography

      • Tyler S. Ralston, Daniel L. Marks, Adeel Ahmad, Stephen A. Boppart
      Pages 407-436
    12. DSP Technology and Methods for OCT

      • Murtaza Ali, Adeel Ahmad, Stephen A. Boppart
      Pages 437-458
    13. OCT Motion Correction

      • Martin F. Kraus, Joachim Hornegger
      Pages 459-476
    14. Image Processing in Intravascular OCT

      • Zhao Wang, David L. Wilson, Hiram G. Bezerra, Andrew M. Rollins
      Pages 477-504
    15. Superluminescent Diode Light Sources for OCT

      • Vladimir R. Shidlovski
      Pages 505-526

About this book

Optical coherence tomography (OCT) is the optical analog of ultrasound imaging and is a powerful imaging technique that enables non-invasive, in vivo, high resolution, cross-sectional imaging in biological tissue.  Between 30 to 40 Million OCT imaging procedures are performed per year in ophthalmology.  The overall market is estimated at more than 0.5 Billion USD. 
A new generation OCT technology was developed, dramatically increasing resolution and speed, achieving in vivo optical biopsy, i.e. the visualization of tissue architectural morphology in situ and in real time.  Functional extensions of OCT technology enable non-invasive, depth resolved functional assessment and imaging of tissue. 
The book introduces OCT technology and applications not only from an optical and technological viewpoint, but also from the biomedical and clinical perspective. This second edition is widely extended and covers significantly more topics then the first edition of this book. The chapters are written leading international research groups, in a style comprehensible to a broad audience.  It will be of interest not only to physicists, scientists and engineers, but also to biomedical and clinical researchers from different medical specialties.


  • Holographic Optical Coherence Imaging
  • Light-tissue Interaction
  • Medical Imaging
  • Non-invasive Optical Imaging
  • OCT Systems Data Analysis and Signal Postprocessing
  • Optical Biopsy
  • Optical Coherence Tomography
  • Optical Microangiography
  • Optophysiology
  • Phase-resolved Imaging of Cellular Morphology


“Optical Coherence Tomography (OCT) is an exciting, comprehensive, perspicuous and highly recommended book that describes the theory, the instrumentation and the disparate applications of OCT. … The theory and the instruments are fully described, the multitude of multicolored figures are clear, and the references are extensive … .” (Barry R. Masters, Optics and Photonic News, January, 2016)

Editors and Affiliations

  • Center for Medical Physics and Biomedical Engineering, Medical University Vienna, General Hospital Vienna, Vienna, Austria

    Wolfgang Drexler

  • Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, USA

    James G. Fujimoto

About the editors

Wolfgang Drexler received his MS and PhD in Electrical Engineering in 1991 and 1995, respectively, at the Technical University of Vienna, Austria. From 2006 to 2009 he was a Full Professor of Biomedical Imaging at the School of Optometry and Vision Sciences at Cardiff University, Wales, UK. Since 2010 he is an Honorary Distinguished Professor at Cardiff University, UK. Since October 2009 he is a Full Professor of Medical Physics and the Head of the Center for Medical Physics and Biomedical Engineering at the Medical University of Vienna, Austria and is also Director of the Christian Doppler Laboratory for Laser Development and their Application in Medicine since 2011.

He spent 2 years at the Massachusetts Institute of Technology (MIT), Cambridge, USA, received the Austrian START Award from the Austrian Science Fund in 2001, the COGAN Award from ARVO in 2007, the Fear Memorial Award in 2008, the Gabriel Coscas Medal in 2009, the EVER Acta Silver Medal in 2010, the DOG’s Innovator’s Award in 2011 as well as the Edridge Green Medal from The Royal College of Ophthalmologists in 2012.

He is a member of the Austrian Academy of Science and has published more than 160 publications (including Nature Medicine and PNAS) in peer reviewed journals and is first, co-author or corresponding author of more than 400 conference proceedings or abstracts resulting in a h-index of 49.  His group’s publications have been cited more than 7700 times in the last 10 years with more than 900 citations in years 2008, 2010 and 2011. He is (Co)Editor of 11 books, including “Optical Coherence Tomography: Technology and Applications” (2008). Wolfgang Drexler gave more than 160 invited or keynote talks since 2000 and has accomplished more than € 9.4 million research grant income in the last decade.

Bibliographic Information

Buying options

USD 349.99
Price excludes VAT (USA)
  • ISBN: 978-3-319-06419-2
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Hardcover Book
USD 399.99
Price excludes VAT (USA)