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  • Living reference work
  • © 2022

Biomarkers in Toxicology

  • Provides an unique comprehensive guide on methods for detecting toxicity in the human body

  • Each chapter features key facts summarizing the most important points

  • A must-have for researchers in biomedicine as well as clinicians, scientists in forensics and pharmacologists.

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Table of contents (50 entries)

  1. Anogenital Distance: Features, Measures, and Uses as a Biomarker for Toxicity In Utero

    • Terje Svingen, Ulla Hass, Camilla L. Schwartz, Sofie Christiansen
  2. Antibodies as Biomarkers: Effect of Microcystin Exposure

    • Alejandro Ferrari, Marcia Andrea Ruiz, Ana Laura Ruibal-Conti
  3. Biomarkers for Assessing Mycotoxin Exposure and Health Effects

    • Carlos Augusto Fernandes de Oliveira, Larissa Tuanny Franco, Amir Ismail
  4. Biomarkers in the Biomonitoring of Fluoride Toxicity: An Overview

    • Maria Karolina Martins Ferreira, José Mário Matos Sousa, Vinicius Ruan Neves dos Santos, Paula Beatriz Oliveira Nunes, Leonardo Oliveira Bittencourt, Senda Charone et al.
  5. Biomarkers of Alcohol Toxicity

    • Natalia Kurhaluk, Halyna Tkachenko
  6. Biomarkers of Antibiotic Toxicity: A Focus on Metronidazole

    • Moses W. Bariweni, Vinood B. Patel, Gulrez M. Zariwala, Raymond I. Ozolua
  7. Biomarkers of Cardiopulmonary Injury and Impact of Bromine Toxicity

    • Ginette Bordcoch, Juan Xavier Masjoan Juncos
  8. Biomarkers of Lead Exposure: Platforms and Analysis

    • Kelly Polido Kaneshiro Olympio, Fernanda Junqueira Salles, Naomi Akiba, Maciel Santos Luz
  9. Biomarkers of Neurotoxicity

    • Alicja Maciejska, Alicja Skórkowska, Jakub Jurczyk, Bartosz Pomierny, Bogusława Budziszewska
  10. Biomarkers of PM2.5 Exposure: Use of Metabolomics as a Platform

    • Minjie Chen, Wei Wei, Lin Tang, Yuhao Zhang, Zhekang Ying
  11. Biomarkers of the Toxic Effects of Chemotherapeutic Agents: A Focus on Antimalarials

    • Audu David, Lucy Petagine, Olufunmilayo Ajoke Idowu, Vinood B. Patel, Adewunmi Babatunde Idowu
  12. Bleaching Agents as Toxic Compounds and Biomarkers of Damage

    • Zeyneb Merve Ozdemir, Derya Surmelioglu
  13. Bovine Whole Blood Cells as a Biomarker Platform for Biological Toxicology: A Focus on Thiacloprid

    • Martina Galdíková, Beáta Holečková, Viera Schwarzbacherová
  14. Contrast-Induced Nephropathy (CIN) and Biomarkers

    • Georgios Georgiadis, Anca Oana Docea, Daniela Calina, Aristidis Tsatsakis, Charalampos Mamoulakis
  15. Different Mice Strains in Biomarker Responses to Toxic Agents: The Example of Acetaminophen

    • Lorena Bavia, Izonete Cristina Guiloski, Milena Carvalho Carneiro, Maritana Mela Prodocimo

About this book

This handbook of the series Biomarkers in Disease informs comprehensively about all aspects of monitoring and detecting toxicity in the human body and model organisms. Biomarkers for assessing toxicity in diverse organs are presented and different assays and methods are explained. Single compounds and drugs and their toxicity for humans are shown and the methods for detection described.

Similar to all the volumes of the Biomarkers in Disease series, the chapters are written by experts in their field, each chapter features key facts summarizing the most important aspects of its respective topic and the definitions of words and terms facilitate the reading and understanding.  

This handbook is a must-have for researchers in toxicology and biomedicine that analyze the effects of drugs and various other substances in the human body and in model organisms, and will serve as a thorough guide for clinicians and pharmacologists.

Keywords

  • biomarkers in toxicity studies
  • skin toxicity
  • nutritional toxicity
  • Challenge-comet assay
  • CRISPR/Cas9 whole genome screens
  • Apoptotic biomarkers
  • oxidative stress markers
  • nanoparticle-induced toxicity
  • iPSCs as biomarkers
  • trastuzumab and toxicity
  • anti-inflammatory biomarkers
  • Urinary biomarkers
  • blood brain barrier as biomarker
  • alcohol toxicity
  • Hair metabolomics
  • drugs and toxicity
  • heavy metals in blood
  • hepatotoxicity
  • DNA adducts

Editors and Affiliations

  • Department of Biomedical Sciences, University of Westminster, London, United Kingdom

    Vinood B. Patel

  • Sch Biomed & Health Sci, Wilkins Bldg, King's College London Franklin, London, United Kingdom

    Victor R. Preedy

  • Department of Medicine, King Abdulaziz Med City, Riyadh, Saudi Arabia

    Rajkumar Rajendram

About the editors

Vinood B. Patel, BSc, PhD, FRSC, is a Reader in Clinical Biochemistry at the University of Westminster.  Dr Patel graduated from the University of Portsmouth with a degree in Pharmacology and completed his PhD in protein metabolism from King’s College London in 1997. His postdoctoral work was carried out at Wake Forest University Baptist Medical School studying structural-functional alterations to mitochondrial ribosomes, where he developed novel techniques to characterize their biophysical properties. In 2014, he was elected as a Fellow to The Royal Society of Chemistry. Dr Patel is a nationally and internationally recognized researcher and was involved in several NIH-funded biomedical grants related to disease. Dr Patel has extensively published biomedical books in the area of diet, biomarkers, toxicology, nutrition and health prevention.

 

Victor R. Preedy PhD, DSc, FRSC, FRSB, FRSPH, FRCPath is Professor of Clinical Biochemistry and Pathology in King’s College Hospital and Emeritus Professor of Nutritional Biochemistry in King’s College London. Professor Preedy graduated in 1974 with a Combined Honours Degree in Biology and Physiology with Pharmacology. He gained his Ph.D. in 1981, in the field of nutrition and metabolism, from the London School of Hygiene and Tropical Medicine, University of London. His second doctorate was awarded for his work on protein metabolism, with a focus on toxicity.   Professor Preedy is a Fellow to four Royal Colleges and has published over 700 articles, including abstracts, peer-reviewed works, reviews and books.

 

Rajkumar Rajendram, AKC, BSc (Hons), MBBS (Dist), EDIC, FRCP Lond is a Consultant at King Abdulaziz Medical City, and Joint Appointment Assistant Professor of Medicine at King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia. In 2001, Dr Rajendram graduated with honours from King’s College, London. He then trained in general medicine and intensive care in Oxford, attaining membership of the Royal College of Physicians (MRCP) in 2004, and becoming a Consultant at the John Radcliffe Hospital, Oxford, in 2011. Dr Rajendram also trained in anaesthesia and became a fellow of the Royal College of Anaesthetists (FRCA) in 2009, and a fellow of the Faculty of Intensive Care Medicine (FFICM) in 2014. During his medical training was also a visiting lecturer at King’s College London; devoting significant time and effort into research on toxicology and nutrition. He has published over 300 textbook chapters, review articles, peer-reviewed papers, and abstracts.

 

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