Table of contents

  1. Front Matter
    Pages i-xvii
  2. Historical Background

    1. Front Matter
      Pages 1-1
    2. Ivelin Pantchev, Goritsa Rakleova, Atanas Pavlov, Atanas Atanassov
      Pages 3-37
    3. Svetla Yancheva, Violeta Kondakova
      Pages 39-63
  3. Metabolic Phytochemistry

    1. Front Matter
      Pages 65-65
    2. Strahil Berkov, Liliya Georgieva, Borjana Sidjimova, Milena Nikolova
      Pages 67-83
    3. Blaga Mutafova, Pedro Fernandes, Sava Mutafov, Strahil Berkov, Atanas Pavlov
      Pages 85-124
  4. Secondary Metabolites

    1. Front Matter
      Pages 125-125
    2. Dominique Laurain-Mattar, Agata Ptak
      Pages 203-223
    3. Heriberto Vidal-Limon, Raúl Sanchez-Muñoz, Abbas Khojasteh, Elisabeth Moyano, Rosa M. Cusido, Javier Palazon
      Pages 295-316
    4. Mariam Gaid, Thomas Wucherpfennig, Stephan Scholl, Ludger Beerhues, Rainer Krull
      Pages 317-341
    5. Radka Vrancheva, Nadezhda Petkova, Ivan Ivanov
      Pages 361-392
  5. Bioreactor Technology and Monitoring

    1. Front Matter
      Pages 411-411
    2. Sören Werner, Rüdiger W. Maschke, Dieter Eibl, Regine Eibl
      Pages 413-432
    3. Juliane Steingroewer, Christiane Haas, Katja Winkler, Carolin Schott, Jost Weber, Julia Seidel et al.
      Pages 433-481
    4. Shakti Mehrotra, Sonal Mishra, Vikas Srivastava
      Pages 483-506
  6. Other Applications

    1. Front Matter
      Pages 507-507
    2. Jianfeng Xu, Melissa Towler, Pamela J. Weathers
      Pages 509-548
    3. Anrini Majumder, Smita Ray, Sumita Jha
      Pages 549-572
  7. Back Matter
    Pages 573-589

About this book


This handbook presents how plant in vitro technologies can overcome current limitations in the production of important plant-derived substances. It explains the advantages of plant in vitro technologies, notably the independence from climatic and soil conditions and the ability to synthesize diverse bioactive substances under controlled conditions. Apart from making diverse metabolites, which can be used e.g. as pharmaceuticals, agrochemicals, flavors, colors, biopesticides or food additives, more easily and more efficiently available, the methods described in this handbook also offer the advantage that rare and threatened plants, which provide access to interesting and desired substances, can be better protected, when the substances are harvested from suitable plant in vitro systems. In times of increasing demand for natural plant-derived products, the described methodologies will be key to ensuring efficient and sustainable access to plant-derived products. They will also help and support in the research and investigation of plant secondary metabolites.

Despite these advantages, still only few substances are being produced at industrial scale by in vitro plant cell cultivation systems to date. This handbook therefore advertises the recent achievements and research in the field, focused on solving limitations in yield and bioprocessing conditions. Leading experts summarize the methodology, which can help overcome drawbacks like low yields of target products or problems associated with the cultivation in bioreactors. Readers will find comprehensive information on fundamentals for using different types of plants in vitro as matrix for sustainable production of valuable secondary metabolites. The handbook summarizes the core information on phytochemistry, bioreactor technology and monitoring of plant cells and tissues in bioprocesses. It also discusses selected applications and safety assessment of food and cosmetic ingredients from plant cell and tissue.


Plant cells Plant biotechnology Plant tissue Plant secondary metabolites biotransformation Bioreactor cultivation Process monitoring and optimization Plant organ cultures Production of bioactive compounds Hairy roots cultures Plant cell cultivation Secondary metabolites yield improvement Bioreactor technology Medicinal and aromatic plants

Editors and affiliations

  • Atanas Pavlov
    • 1
  • Thomas Bley
    • 2
  1. 1.University of Food TechnologiesPlovdivBulgaria
  2. 2.Bioprocess EngineeringInstitute of Food Technology and Bioprocess Engineering, TU DresdenDresdenGermany

Bibliographic information