Table of contents

  1. Front Matter
    Pages i-xix
  2. Introduction to the Endocrine System

    1. Front Matter
      Pages 1-1
    2. Angela M. Leung, Alan P. Farwell
      Pages 3-25
  3. Hormone Synthesis, Secretion, and Transport

    1. Front Matter
      Pages 27-27
    2. Noemi Malandrino, Robert J. Smith
      Pages 29-42
    3. Filippo Acconcia, Maria Marino
      Pages 43-72
  4. Hormone Receptors and Signal Transduction Processes

    1. Front Matter
      Pages 83-83
    2. Hanna Pincas, Javier González-Maeso, Frederique Ruf-Zamojski, Stuart C. Sealfon
      Pages 85-120
    3. Andrew J. Brooks, Farhad Dehkhoda, Birthe B. Kragelund
      Pages 157-185
    4. Xuguang Zhu, Sheue-yann Cheng
      Pages 233-257
    5. Sandra Incerpi, Paul J. Davis, Jens Z. Pedersen, Antonia Lanni
      Pages 259-284
  5. The Classical Endocrine System and Endocrine Glands

    1. Front Matter
      Pages 285-285
    2. Linda Johnston Rohrbasser, Hussain Alsaffar, Joanne Blair
      Pages 287-321
    3. Joseph G. Verbalis
      Pages 323-351
    4. Trevor E. Angell, Stephen A. Huang, Erik K. Alexander
      Pages 353-366
    5. Christopher S. Kovacs
      Pages 367-386
    6. Filippo Ceccato, Carla Scaroni, Marco Boscaro
      Pages 387-421
    7. Salvatore Piro, Francesca Urbano, Franco Folli, Giovanna Finzi, Lorella Marselli, Piero Marchetti
      Pages 423-454
    8. Alessandro Ilacqua, Davide Francomano, Antonio Aversa
      Pages 455-491
    9. M. O. Verhoeven, C. B. Lambalk
      Pages 493-514
  6. Nonclassical Endocrine Organs

    1. Front Matter
      Pages 515-515
    2. Jens F. Rehfeld
      Pages 517-531
    3. Adolfo J. de Bold, John C. Burnett Jr., Jens Peter Goetze
      Pages 533-558
    4. Mathieu Ferron
      Pages 559-585
  7. The Regulatory Role of Endocrine System

    1. Front Matter
      Pages 587-587
    2. Valentina Lo Preiato, Valentina Vicennati, Alessandra Gambineri, Uberto Pagotto
      Pages 589-610
    3. Massimo Mannelli, Gian Paolo Rossi, Paul-Emmanuel Vanderriele, Gabriele Parenti
      Pages 611-625
    4. Sara A. DiVall, Carolina DiBlasi
      Pages 627-658
    5. Kelly Kuo, David Hackney, Sam Mesiano
      Pages 659-690
    6. Changhan D. Lee, Valter D. Longo
      Pages 691-702
    7. Elizabeth Lowden, Peter Kopp
      Pages 703-725
    8. Fady Hannah-Shmouni, Constantine A. Stratakis
      Pages 727-763
  8. Back Matter
    Pages 787-796

About this book


This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.


Endocrine and metabolic regulation Endocrine physiology Endocrine system Hormone regulation and action Molecular endocrinology

Editors and affiliations

  • Antonino Belfiore
    • 1
  • Derek LeRoith
    • 2
  1. 1.Magna Graecia UniversityCatanzaroItaly
  2. 2.Icahn School of Medicine at Mt. SinaiNew YorkUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Reference Module Medicine
  • Print ISBN 978-3-319-44674-5
  • Online ISBN 978-3-319-44675-2
  • Series Print ISSN 2510-1927
  • Series Online ISSN 2510-1935
  • Buy this book on publisher's site