Table of contents

  1. Front Matter
    Pages 1-1
  2. Epidemiology

    1. Front Matter
      Pages 1-1
    2. Rexford S. Ahima
      Pages 3-12
    3. Kristina H. Lewis, Sanjay Basu
      Pages 13-31
    4. Pablo Aschner
      Pages 33-39
    5. Charles Agyemang, Sandra Boatemaa, Grace Agyemang Frempong, Ama de-Graft Aikins
      Pages 41-53
    6. Zlatko Nikoloski, Gemma Williams
      Pages 55-72
    7. Mohsin Wali, C. Venkata S. Ram
      Pages 73-85
    8. Yong-Moon Mark Park, Junxiu Liu
      Pages 87-100
  3. Genetic Factors

    1. Front Matter
      Pages 101-101
    2. John R. Speakman
      Pages 103-122
    3. Alexis C. Frazier-Wood, Zhe Wang
      Pages 123-140
    4. Struan F. A. Grant
      Pages 141-157
    5. Nora L. Nock
      Pages 159-193
    6. Piers R. Blackett, Dharambir K. Sanghera
      Pages 195-219
  4. Environmental Factors

    1. Front Matter
      Pages 221-221
    2. Catherine E. Aiken
      Pages 223-242
    3. Sheryl O. Hughes, Thomas G. Power, Jayna M. Dave, Teresia M. O’Connor
      Pages 243-259
    4. Andrea Garfinkel-Castro, Keuntae Kim, Shima Hamidi, Reid Ewing
      Pages 275-286
    5. Jacques Demongeot, Adrien Elena, Carla Taramasco
      Pages 287-307
  5. Pathophysiology

    1. Front Matter
      Pages 309-309
    2. Rexford S. Ahima
      Pages 311-326
    3. Jose E. Galgani, Víctor Cortés, Fernando Carrasco
      Pages 327-346
    4. Martin G. Myers Jr., David P. Olson, Malcolm J. Low, Carol F. Elias
      Pages 347-368
    5. Vivian Peirce, Vanessa Pellegrinelli, Antonio Vidal-Puig
      Pages 369-396
    6. Rexford S. Ahima, Laura M. Scolaro, Hyeong-Kyu Park
      Pages 397-421
    7. Elizabeth G. Mietlicki-Baase, Matthew R. Hayes
      Pages 423-445
    8. Herbert Tilg, Alexander R. Moschen
      Pages 447-459
    9. Yajuan Qi, Xiaoqin Guo, Shaodong Guo
      Pages 479-504
    10. Maeve A. McArdle, Elaine B. Kennedy, Helen M. Roche
      Pages 505-524
    11. Dick C. Chan, Jing Pang, Gerald F. Watts
      Pages 525-540
    12. Bente Klarlund Pedersen
      Pages 541-554
    13. Edith Grosbellet, Etienne Challet
      Pages 555-575
  6. Diseases Associated with Obesity

    1. Front Matter
      Pages 577-577
    2. David R. Weber, Babette S. Zemel
      Pages 579-599
    3. Carrie Burns, Imali Sirisena
      Pages 601-617
    4. Martin A. Alpert
      Pages 619-639
    5. Elisabeth Smolle, Sonja M. Kessler, Nicole Golob, Johannes Haybaeck
      Pages 641-657
    6. Sravanthi Parasa, Arun Raghav Mahankali Sridhar
      Pages 659-664
    7. John A. Batsis
      Pages 665-678
    8. Silke Ryan, Walter T. McNicholas
      Pages 679-692
    9. Ashley A. Martin
      Pages 709-722
    10. Ivana Vucenik, Laundette P. Jones, John C. McLenithan
      Pages 723-741
    11. Hyeong-Kyu Park, Rexford S. Ahima
      Pages 743-759
    12. Jeffrey H. William, Holly Kramer, Sylvia E. Rosas
      Pages 761-780
  7. Prevention and Treatment

    1. Front Matter
      Pages 781-781

About this book


This comprehensive reference work edited by one of the leading authorities on obesity presents an up-to-date survey of the current scientific understanding of the metabolic syndrome, as well as an overview of the most significant changes to the field over the past 30 years. This volume is a thorough reference for obesity and the metabolic syndrome and will prove an indispensable resource for clinicians and researchers at levels worldwide.​ The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on behaviors that lead to obesity, in particular to over consumption of energy-dense food and to sedentary lifestyle. However, obesity is an extremely complex condition with poorly defined pathogenesis. In addition, when combined with other comorbidities such as hypertension and dyslipidemia, obesity often leads to a patient diagnosis of metabolic syndrome, a very troubling condition that has grown, and is continuing to grow, rapidly each year in prevalence worldwide. Metabolic syndrome is a cluster of conditions — increased blood pressure, a high blood sugar level, excess body fat around the waist and abnormal cholesterol levels — that occur together, increasing one’s risk of heart disease, stroke and diabetes. This resource covers the full range of scientific and clinical aspects: epidemiology, genetics, environmental factors, pathophysiology, diseases associated with obesity, and clinical management.


Clinical Management Epidemiology Metabolic Syndrome Obesity Pathophysiology

Editors and affiliations

  • Rexford S. Ahima
    • 1
    • 2
  1. 1.Division of Endocrinology, Diabetes and Metabolism, Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaUSA
  2. 2.Institute for Diabetes, Obesity and MetabolismUniversity of PennsylvaniaPhiladelphiaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-11250-3
  • Online ISBN 978-3-319-11251-0
  • Buy this book on publisher's site