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Multivariate Data Analysis of Proteome Data

  • Kåre Engkilde
  • Susanne Jacobsen
  • Ib Søndergaard
Part of the Methods in Molecular Biology book series (MIMB, volume 355)

Abstract

We present the background for multivariate data analysis on proteomics data with a hands-on section on how to transfer data between different software packages. The techniques can also be used for other biological and biochemical problems in which structures have to be found in a large amount of data. Digitalization of the 2D gels, analysis using image processing software, transfer of data, multivariate data analysis, interpretation of the results, and finally we return to biology.

Key Words

Multivariate data analysis proteomics 2D-electrophoresis 2D-gels PCA PLSR image processing 

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Copyright information

© Humana Press Inc., Totowa, NJ 2007

Authors and Affiliations

  • Kåre Engkilde
    • 1
  • Susanne Jacobsen
    • 1
  • Ib Søndergaard
    • 1
  1. 1.BioCentrum-DTU, Biochemistry and Nutrition GroupTechnical University of DenmarkLyngbyDenmark

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