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Natural Products Isolation pp 1–25Cite as

Natural Product Isolation

An Overview

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Part of the book series: Methods in Biotechnology ((MIBT,volume 20))

Summary

There has been a remarkable resurgence of interest in natural product research over the last decade or so. With the outstanding developments in the areas of separation science, spectroscopic techniques, and microplate-based ultrasensitive in vitro assays, natural product research is enjoying renewed attention for providing novel and interesting chemical scaffolds. The various available hyphenated techniques, e.g., GC-MS, LC-PDA, LC-MS, LC-FTIR, LC-NMR, LC-NMR-MS, CE-MS, have made possible the preisolation analyses of crude extracts or fractions from different natural sources, isolation and on-line detection of natural products, chemotaxonomic studies, chemical finger printing, quality control of herbal products, dereplication of natural products, and metabolomic studies. While different chapters in this book are devoted to a number of specific aspects of natural product isolation protocols, this chapter presents, with practical examples, a general overview of the processes involved in natural product research, starting from extraction to determination of the structures of purified products and their biological activity.

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Author information

Authors and Affiliations

  1. Pharmaceutical Biotechnology Research Group, School of Biomedical Sciences, University of Ulster at Coleraine, Coleraine, Northern Ireland, UK

    Satyajit D. Sarker

  2. Molecular Nature Limited, Plas Gogerddan, Aberystwyth, Wales, UK

    Zahid Latif

  3. Phytochemistry Research Laboratories, Department of Pharmaceutical Sciences, University of Strathcyclde, Glasgow, Scotland, UK

    Alexander I. Gray

Authors
  1. Satyajit D. Sarker
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  2. Zahid Latif
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  3. Alexander I. Gray
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Editor information

Editors and Affiliations

  1. Pharmaceutical Biotechnology Research Group school of Biomedical Sciences, University of Ulster at Coleraine, Coleraine, Northern Ireland, UK

    Satyajit D. Sarker

  2. Molecular Nature Limited Plas Gogerddan, Aberystwyth, Wales, UK

    Zahid Latif

  3. Phytochemistry Research Lab Department of Pharmaceutical Sciences, University of Strathclyde, Glasgow, Scotland, UK

    Alexander I. Gray

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© 2006 Humana Press Inc., Totowa,NJ

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Sarker, S.D., Latif, Z., Gray, A.I. (2006). Natural Product Isolation. In: Sarker, S.D., Latif, Z., Gray, A.I. (eds) Natural Products Isolation. Methods in Biotechnology, vol 20. Humana Press. https://doi.org/10.1385/1-59259-955-9:1

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  • DOI: https://doi.org/10.1385/1-59259-955-9:1

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-447-0

  • Online ISBN: 978-1-59259-955-4

  • eBook Packages: Springer Protocols

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